Stridor in Children Dr Montaha AL-Iede, MD, DCH, FRCP

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Presentation transcript:

Stridor in Children Dr Montaha AL-Iede, MD, DCH, FRCP Paediatric Pulmonologist & Sleep physician

Stridor is a harsh, vibratory sound of variable pitch caused by partial obstruction of the respiratory passages that results in turbulent airflow through the airway. Stridor is a sign of upper airway obstruction. laryngomalacia is the most common cause of chronic stridor. Croup is the most common cause of acute stridor.

An inspiratory stridor suggests airway obstruction above the glottis. An expiratory stridor is indicative of obstruction in the lower trachea. A biphasic stridor suggests a glottic or subglottic lesion. Laryngeal lesions often result in voice changes.

Causes of Stridor in Children According to Site of Obstruction Nose and pharynx Choanal atresia Lingual thyroid or thyroglossal cyst Macroglossia Micrognathia Hypertrophic tonsils/adenoids Retropharyngeal or peritonsillar abscess

Larynx Laryngomalacia Laryngeal web, cyst or laryngocele Laryngotracheobronchitis (viral croup) Acute spasmodic laryngitis (spasmodic croup) Epiglottitis Vocal cord paralysis Laryngotracheal stenosis Intubation Foreign body Cystic hygroma Subglottic hemangioma

Trachea Tracheomalacia Bacterial tracheitis External compression

Laryngomalacia (chronic stridor) Is the most common cause of chronic stridor in children younger than two years. It has a male-to-female ratio of approximately 2:1. The condition is due to an intrinsic defect or delayed maturation of supporting structures of the larynx. The airway is partially obstructed during inspiration by the prolapse of the flaccid epiglottis, arytenoids and aryepiglottic folds. The inspiratory stridor is usually worse when the child is in a supine position, when crying or agitated, or when an upper respiratory tract infection occurs

Laryngotracheobronchitis (Viral Croup) (acute stridor) The most common cause of acute stridor in childhood. The condition is caused most commonly by parainfluenza virus, but it can also be caused by influenza virus types A or B, RSV and rhinoviruses. Croup usually occurs in children 6 months to 6 years of age, with a peak incidence in the second year of life. The male-to-female ratio is approximately 3:2.4

Is usually preceded by an upper respiratory tract infection of several days' duration. A low-grade fever, barking cough, inspiratory stridor and hoarseness then develop. Symptoms are characteristically worse at night and are aggravated by agitation and crying.

Epiglottitis (acute stridor) True Medical Emergency In children, epiglottitis is almost always caused by Haemophilus influenzae type b. In recent years, the occurrence of epiglottitis has been reduced dramatically by the widespread use of the H. influenzae type b vaccine. Epiglottitis usually occurs in children 2-7 years of age, with a peak incidence in three-year-olds

The male-to-female ratio is approximately 3:2. The disease is characterized by an abrupt onset of high fever, toxicity, agitation, stridor, dyspnea, muffled voice, dysphagia and drooling. The older child may prefer to sit leaning forward with the mouth open and the tongue somewhat protruding. An edematous, cherry red epiglottis, visualized in a controlled environment, is the hallmark of epiglottitis.

Vocal Cord Paralysis Unilateral vocal cord paralysis occurs more often on the left side because of the longer course of the recurrent laryngeal nerve, which makes it more vulnerable to injury. Unilateral dysfunction may result from birth trauma, trauma during thoracic surgery or compression by mediastinal masses of cardiac, pulmonary, esophageal, thyroid or lymphoid origin

Bilateral vocal cord paralysis is more commonly associated with central nervous system problems including perinatal asphyxia, cerebral hemorrhage, hydrocephalus, bulbar injury and Arnold-Chiari malformation. The vocal cords may also be injured by direct trauma from endotracheal intubation attempts or during deep airway suction.

In vocal cord paralysis, the stridor is typically biphasic. In unilateral vocal cord paralysis, the infant's cry is weak and feeble; however, there is usually no respiratory distress. In bilateral vocal cord paralysis, the voice is usually of good quality, but there is marked respiratory distress

Tracheomalacia (chronic stridor) Characterized by abnormal tracheal collapse secondary to inadequate cartilaginous and myoelastic elements supporting the trachea. Tracheal narrowing occurs with expiration and causes stridor. The stridor may not be present at birth but appears insidiously after the first weeks of life. The stridor is usually aggravated by respiratory tract infections and agitation.

Bacterial Tracheitis (acute stridor) Is usually caused by Staphylococcus aureus, although it can also be caused by H. influenzae type b and Moraxella catarrhalis. Most patients are younger than 3 years of age. Bacterial tracheitis usually follows an upper respiratory tract infection. The patient then becomes seriously ill with high fever, toxicity and respiratory distress.

Retropharyngeal abscess: ( acute stridor) Complication of bacterial pharyngitis Younger than 6 years Abrupt onset of high fever, difficulty swallowing , refusing to feed , sore throat , hyperextension of the neck, and respiratory distress.

Clinical Evaluation Historical Information in the Evaluation of Stridor in Children HISTORICAL DATA POSSIBLE ETIOLOGY Age of onset Birth Vocal cord paralysis, congenital lesions such as choanal atresia, laryngeal web and vascular ring 4 to 6 weeks Laryngomalacia 1 to 4 years Croup, epiglottitis, foreign body aspiration Chronicity Acute onset Foreign body aspiration, infections such as croup and epiglottitis Long duration Structural lesion such as laryngomalacia, laryngeal web or larynogotracheal stenosis

Precipitating Factors Worsening with straining or crying Laryngomalacia, subglottic hemangioma Worsening in a supine position Laryngomalacia, tracheomalacia, macroglossia, micrognathia Worsening at night Viral or spasmodic croup Worsening with feeding Tracheoesophageal fistula, tracheomalacia, neurologic disorder, vascular compression Antecedent upper respiratory tract infection Croup, bacterial tracheitis Choking Foreign body aspiration, tracheoesophageal fistula

Associated symptoms Barking cough Croup Brassy cough Tracheal lesion Drooling Epiglottitis, foreign body in esophagus, retropharyngeal or peritonsillar abscess Weak cry Laryngeal anomaly or neuromuscular disorder Muffled cry Supraglottic lesion Hoarseness Croup, vocal cord paralysis Snoring Adenoidal or tonsillar hypertrophy Dysphagia

Past health Endotracheal intubation Vocal cord paralysis, laryngotracheal stenosis Birth trauma, perinatal asphyxia, cardiac problem Vocal cord paralysis Atopy Angioneurotic edema, spasmodic croup Family history Down syndrome Hypothyroidism

Physical Examination Findings in the Evaluation of Stridor in Children PHYSICAL FINDINGS POSSIBLE ETIOLOGY General Cyanosis Cardiac disorder, hypoventilation with hypoxia Fever Underlying infection Toxicity Epiglottitis Tachycardia Cardiac failure Bradycardia Hypothyroidism Quality of stridor Inspiratory stridor Obstruction above glottis Expiratory stridor Obstruction at or below lower trachea Biphasic stridor Glottic or subglottic lesion

Position of the child Hyperextension of the neck Extrinsic obstruction at or above larynx Leaning over, drooling Epiglottitis Lessening of stridor in prone position Laryngomalacia

Chest findings Prolonged inspiratory phase Laryngeal obstruction Prolonged expiratory phase Tracheal obstruction Unilateral decreased air entry Foreign body in ipsilateral bronchus

Associated signs Arrhythmias, significant heart murmurs, abnormal heart sounds Structural heart disease Cutaneous hemangiomas Subglottic hemangioma Peripheral neuropathy Vocal cord paralysis Urticaria/angioneurotic edema Angioneurotic edema

Diagnostic Studies AP & Lateral CXR: views of the neck are useful in the assessment of adenoidal and tonsillar size, epiglottic size and shape, retropharyngeal profile and subglottic and tracheal anatomy. detection of radio-opaque foreign body and concomitant pulmonary disease.

Steeple sign

Thumb Sign

Barium swallow is a useful method if vascular compression or gastroesophageal reflux is suspected. Gastrografin should be used as the contrast medium if tracheoesophageal fistula is suspected.: Bronchoscopy/ flexible or rigid: Airway malacia CT neck and chest

Management ABC According to the cause

THANK YOU