Repetition time (TR) and T1-weighting.

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Repetition time (TR) and T1-weighting. Repetition time (TR) and T1-weighting. Consider the following example in which two tissues, fat and fluid are being imaged where fat has shorter transverse and longitudinal relaxation times than fluid. An initial 90° radiofrequency (RF) pulse is switched on and off, time passes (TR), a second 90° RF pulse is switched on and off, MR signal is then sampled and an image is generated. As MR signal sampling occurs after the switching off of the second RF pulse, the signal intensity will be determined by the amount of transverse magnetisation at that point. This in turn will be governed by the value of longitudinal magnetisation of the two tissues immediately before the second 90° RF pulse is switched on. Choosing a long TR (eg, 1500 msec) would allow the tissues to recover their longitudinal magnetisation fully with no appreciable difference in the value of longitudinal magnetisation existing between the tissues. In this situation, the application of a second RF pulse with subsequent MR signal sampling would result in no discernible difference in MR signal between the tissues as the transverse magnetisation values for the tissues are essentially equal (A) (ie, no signal contrast). Choosing a short TR (20 msec) means that at the time of applying a second 90° RF pulse tissues with a long T1 (fluid) will show less recovery in longitudinal magnetisation than tissues with a short T1 (fat). The tissues will possess different transverse magnetisation values (B) and, thus, will generate different signal intensities and allow greater contrast between tissues (C). This figure is only reproduced in colour in the online version. Stuart Currie et al. Postgrad Med J 2013;89:209-223 Copyright © The Fellowship of Postgraduate Medicine. All rights reserved.