Comparison of effects of topical levocabastine and nedocromil sodium on the early response in a conjunctival provocation test with allergen Catherine.

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Presentation transcript:

Comparison of effects of topical levocabastine and nedocromil sodium on the early response in a conjunctival provocation test with allergen Catherine Hammann, MDa, Regine Kämmerer, MDa, Martin Gerber, MScb, François Spertini, MDa Journal of Allergy and Clinical Immunology Volume 98, Issue 6, Pages 1045-1050 (December 1996) DOI: 10.1016/S0091-6749(96)80189-8 Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 1 Shifts in allergen concentration for each patient after levocabastine or nedocromil treatment compared with screening phase. Results are expressed as number of shifts in allergen concentration. Levocabastine versus nedocromil p = 0.019 (chi square trend). Journal of Allergy and Clinical Immunology 1996 98, 1045-1050DOI: (10.1016/S0091-6749(96)80189-8) Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 2 Cumulative percent of patients reaching reaction threshold at each allergen concentration level. Journal of Allergy and Clinical Immunology 1996 98, 1045-1050DOI: (10.1016/S0091-6749(96)80189-8) Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 3 Mean erythema (percent) at different allergen concentrations. *Levocabastine versus nedocromil p < 0.05 (Student’s t test) + number of patients when less than 24. Journal of Allergy and Clinical Immunology 1996 98, 1045-1050DOI: (10.1016/S0091-6749(96)80189-8) Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 4 Mean pruritus score (range, 1 to 3) at different allergen concentrations. *Levocabastine versus nedocromil p < 0.05 (Student’s t test) + number of patients when less than 24. Journal of Allergy and Clinical Immunology 1996 98, 1045-1050DOI: (10.1016/S0091-6749(96)80189-8) Copyright © 1996 Mosby, Inc. Terms and Conditions