miR-145 overexpression reduces IGF1-coated bead attachment.

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miR-145 overexpression reduces IGF1-coated bead attachment. miR-145 overexpression reduces IGF1-coated bead attachment. Ishikawa cells were mock-transfected, transfected with a non-targeting control miR-mimic or a miR-145 mimic (10–100 nM) and cultured for 48 h prior to transfer of beads coated in IGF1 (IGF-I) or BSA (negative control). Attachment was assessed after a further 48 h using a scale adapted from Kang et al., 2014. Data are expressed as a percentage of total beads. The box represents the 25–75th percentiles, and the median is indicated. The whiskers show the range. **P<0.01 (n = 5, Kruskal–Wallis test). Youn-Jung Kang et al. J Cell Sci 2015;128:804-814 © 2015. Published by The Company of Biologists Ltd