Mometasone furoate administered once daily is as effective as twice-daily administration for treatment of mild-to-moderate persistent asthma James P.

Slides:

Advertisements

Similar presentations

Efficacy and safety overview of a new inhaled corticosteroid, QVAR (hydrofluoroalkane- beclomethasone extrafine inhalation aerosol), in asthma Jennifer.

Advertisements

W.Travis Cain, MDa, Greg Cable, PhDb, John J. Oppenheimer, MDc

House dust mite avoidance measures improve peak flow and symptoms in patients with allergy but without asthma: A possible delay in the manifestation of.

Double-blind placebo-controlled study of the efficacy of oral terfenadine in the treatment of chronic fatigue syndrome Paul Steinberg, MDa, Bruce E.

Diane J. Pincus, MD, Stanley J. Szefler, MD, Lynn M

F.Estelle R. Simons, MDa, Bruce M. Prenner, MDb, Albert Finn, MDc

Treating acute rhinosinusitis: Comparing efficacy and safety of mometasone furoate nasal spray, amoxicillin, and placebo Eli O. Meltzer, MD, Claus Bachert,

Ulrich Wahn, MDa. ‡, Eli O. Meltzer, MDb. ‡, Albert F. Finn, MDc

Zafirlukast improves asthma symptoms and quality of life in patients with moderate reversible airflow obstruction Robert A. Nathan, MDa, Jonathan A.

A review of the preclinical and clinical data of newer intranasal steroids used in the treatment of allergic rhinitis William R. Lumry, MD Journal of.

Comparative efficacy and anti-inflammatory profile of once-daily therapy with leukotriene antagonist or low-dose inhaled corticosteroid in patients with.

A randomized, vehicle-controlled trial of tacrolimus ointment for treatment of atopic dermatitis in children Mark Boguniewicz, MDa, Virginia C. Fiedler,

Richard L. ZuWallack, MD a,b, James P

Fluticasone furoate nasal spray: A single treatment option for the symptoms of seasonal allergic rhinitis Harold B. Kaiser, MD, Robert M. Naclerio, MD,

Asthma and increased bronchial responsiveness in elite athletes: Atopy and sport event as risk factors Ilkka J. Helenius, MDa, Heikki O. Tikkanen, MDb,

Comparison of once-daily ebastine 20 mg, ebastine 10 mg, loratadine 10 mg, and placebo in the treatment of seasonal allergic rhinitis Paul H. Ratner,

Bruce M. Prenner, MD, Bobby Q. Lanier, MD, David I

Roflumilast combined with montelukast versus montelukast alone as add-on treatment in patients with moderate-to-severe asthma Eric D. Bateman, MD, Udo-Michael.

Badrul A. Chowdhury, MD, PhD

Hydroxychloroquine improves airflow and lowers circulating IgE levels in subjects with moderate symptomatic asthma B.Lauren Charous, MD, Elkan F. Halpern,

Effect of inhaled fluticasone with and without salmeterol on airway inflammation in asthma Annika Wallin, PhDa, Malcolm Sue-Chu, PhDb, Leif Bjermer,

Comparison of the efficacy of budesonide and fluticasone propionate aqueous nasal spray for once daily treatment of perennial allergic rhinitis James.

As-needed use of fluticasone propionate nasal spray reduces symptoms of seasonal allergic rhinitis Albert Jen, MD, Fuad Baroody, MD, Marcy de Tineo,

Adverse effects of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors associated with elevated serum IgE and eosinophilia Carol K. Fosso, MDa,

Harold B. Kaiser, MDa, Steven R. Findlay, MD†, John W

Mark T. S. Chan, MDa, Donald Y. M. Leung, MD, PhDb, Stanley J

Elinor Simons, MDa, William M

Low-dose fluticasone propionate compared with montelukast for first-line treatment of persistent asthma: A randomized clinical trial William Busse, MDa,

Inhaled fluticasone propionate delivered by means of two different multidose powder inhalers is effective and safe in a large pediatric population with.

Low-dose levalbuterol in children with asthma: Safety and efficacy in comparison with placebo and racemic albuterol Henry Milgrom, MDa, David P. Skoner,

Michael Mellon, MD Journal of Allergy and Clinical Immunology

Efficacy and safety of budesonide inhalation suspension (Pulmicort Respules) in young children with inhaled steroid–dependent, persistent asthma Gail.

Increased sensitivity to bradykinin among African Americans

Paul M. O’Byrne, MB, FRCPI, FRCP(C)a, Soren Pedersen, MD, PhDb

A review of the current guidelines for allergic rhinitis and asthma

Physician-targeted program on inhaled therapy for childhood asthma

Correlation between alcohol-induced asthma and acetaldehyde dehydrogenase-2 genotype Atsuko Takao, MDa, Terufumi Shimoda, MDa, Shigeru Kohno, MDa, Sadahiro.

James P. Kemp, MDa, David A. Cook, MDb, Gary A

Inflammatory cells, cytokine and chemokine expression in asthma immunocytochemistry and in situ hybridization Qutayba Hamid, MD, PhD, Editor Journal.

Salmeterol and fluticasone propionate combined in a new powder inhalation device for the treatment of asthma: A randomized, double-blind, placebo-controlled.

Wine-induced asthma: A placebo-controlled assessment of its pathogenesis Hassan Vally, BSc (Hons), Amanda Carr, BAppSc, Jacque El-Saleh, RN, Philip Thompson,

Inhaled mometasone furoate reduces oral prednisone requirements while improving respiratory function and health-related quality of life in patients with.

Budesonide delivered by Turbuhaler is effective in a dose-dependent fashion when used in the treatment of adult patients with chronic asthma William.

Mary Elizabeth Bollinger, DO, Robert G. Hamilton, PhD, Robert A

Subjective and objective assessments in patients with seasonal allergic rhinitis: Effects of therapy with mometasone furoate nasal spray Eli O. Meltzer,

F.Estelle R. Simons, MDa, Bruce M. Prenner, MDb, Albert Finn, MDc

Treating acute rhinosinusitis: Comparing efficacy and safety of mometasone furoate nasal spray, amoxicillin, and placebo Eli O. Meltzer, MD, Claus Bachert,

Fluticasone propionate powder administered through Diskhaler versus triamcinolone acetonide aerosol administered through metered-dose inhaler in patients.

Thomas B. Casale, MDa, I. Leonard Bernstein, MDb, William W

A comparison of multiple doses of fluticasone propionate and beclomethasone dipropionate in subjects with persistent asthma Gordon D. Raphael, MDa, Robert.

News & Notes Journal of Allergy and Clinical Immunology

Fluticasone propionate powder: Oral corticosteroid–sparing effect and improved lung function and quality of life in patients with severe chronic asthma

A placebo- and active-controlled randomized trial of prophylactic treatment of seasonal allergic rhinitis with mometasone furoate aqueous nasal spray

F. Estelle R. Simons, MD, FRCPCa, Xiaochen Gu, PhDb, Keith J

Low-dose inhaled fluticasone propionate versus oral zafirlukast in the treatment of persistent asthma Eugene R. Bleecker, MDa, Michael J. Welch, MDb,

Omalizumab improves asthma-related quality of life in patients with severe allergic asthma Albert Finn, MDa, Gary Gross, MDb, Julius van Bavel, MDc,

A randomized, double-blind trial of the effect of treatment with montelukast on bronchial hyperresponsiveness and serum eosinophilic cationic protein.

The 30th anniversary of the American Board of Allergy and Immunology: Then and now Lynn Des Prez a, Charles E. Reed, MD, Lawrence B. Schwartz, MDb, John.

Steroid-sparing effects of fluticasone propionate 100 μg and salmeterol 50 μg administered twice daily in a single product in patients previously controlled.

Sami T. Remes, MD, MPHa,b, Jose A. Castro-Rodriguez, MDa, Catharine J

Anaphylaxis after initial ingestion of rambutan, a tropical fruit

Efficacy and safety overview of a new inhaled corticosteroid, QVAR (hydrofluoroalkane- beclomethasone extrafine inhalation aerosol), in asthma Jennifer.

Diane J. Pincus, MD, Stanley J. Szefler, MD, Lynn M

Footnotes1 Journal of Allergy and Clinical Immunology

National trends in asthma visits and asthma pharmacotherapy,

Larry C. Borish, MDa, Harold S

Double-blind, placebo-controlled study comparing the efficacy and safety of fexofenadine hydrochloride (120 and 180 mg once daily) and cetirizine in seasonal.

The preventive effect and duration of action of two doses of inhaled furosemide on exercise-induced asthma in children Elio Novembre, MD, Gianfranco.

Asthma symptoms and airway hyperresponsiveness are lower during treatment with nedocromil sodium than during treatment with regular inhaled albuterol

Comparative efficacy and safety of a once-daily loratadine-pseudoephedrine combination versus its components alone and placebo in the management of seasonal.

Presentation transcript:

Mometasone furoate administered once daily is as effective as twice-daily administration for treatment of mild-to-moderate persistent asthma James P. Kemp, MDa, Robert B. Berkowitz, MDb, S.David Miller, MDc, John J. Murray, MD, PhDd, Keith Nolop, MDe, Judy E. Harrison, MDe Journal of Allergy and Clinical Immunology Volume 106, Issue 3, Pages 485-492 (September 2000) DOI: 10.1067/mai.2000.109431 Copyright © 2000 Mosby, Inc. Terms and Conditions

Fig. 1 Effect of MF-DPI treatment on mean change in FEV1. Mean ± SEM changes in FEV1 from baseline at each treatment visit and at endpoint are shown. Squares, MF-DPI 200 μg once daily morning treatment; diamonds, MF-DPI 400 μg once daily morning treatment; triangles, MF-DPI 200 μg twice daily treatment; circles, placebo. *P ≤ .02 versus placebo. Journal of Allergy and Clinical Immunology 2000 106, 485-492DOI: (10.1067/mai.2000.109431) Copyright © 2000 Mosby, Inc. Terms and Conditions

Fig. 2 Effect of MF-DPI treatment on mean change in morning PEF. Mean ± SEM changes in morning PEF from baseline at each treatment visit and at endpoint are shown. Squares, MF-DPI 200 μg once daily morning treatment; diamonds, MF-DPI 400 μg once daily morning treatment; triangles, MF-DPI 200 μg twice daily treatment; circles, placebo. *P < .01 versus MF-DPI 200 μg once daily morning treatment and placebo; +P = .04 versus placebo. Journal of Allergy and Clinical Immunology 2000 106, 485-492DOI: (10.1067/mai.2000.109431) Copyright © 2000 Mosby, Inc. Terms and Conditions

Fig. 3 Effect of MF-DPI treatment on Kaplan-Meier estimates of time to worsening. All MF-DPI treatment groups had a greater probability of remaining in the study (P < .01) compared with placebo. Journal of Allergy and Clinical Immunology 2000 106, 485-492DOI: (10.1067/mai.2000.109431) Copyright © 2000 Mosby, Inc. Terms and Conditions