Ziad A. Massy Kidney International

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Potential strategies to normalize the levels of homocysteine in chronic renal failure patients Ziad A. Massy Kidney International Volume 63, Pages S134-S136 (May 2003) DOI: 10.1046/j.1523-1755.63.s84.28.x Copyright © 2003 International Society of Nephrology Terms and Conditions

Figure 1 Overview of homocysteine metabolism with particular emphasizing of the remethylation pathways: the remethylation pathway by methionine synthase, and an alternative remethylation pathway by betaine-homocysteine methyl transferase. Abbreviations are: Ado, adenosyl; Hcy, homocysteine; DHF, dyhydrofolate; THF, tetrahydrofolate; MTHF, methyltetrahydrofolate; METHF, methylene tetrahydrofolate; SHM, serine hydromethyl; B2, vitamin B2 (riboflavin); B3, vitamin B3 (niacin); B6, vitamin B6 (pyridoxine); B12, vitamin B12. Kidney International 2003 63, S134-S136DOI: (10.1046/j.1523-1755.63.s84.28.x) Copyright © 2003 International Society of Nephrology Terms and Conditions