Wrch-1 localizes to focal adhesions.

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Presentation transcript:

Wrch-1 localizes to focal adhesions. Wrch-1 localizes to focal adhesions. HelaS3 cells were plated and transfected with GFP-Wrch-1 as described in Materials and Methods. Sixteen hours after transfection, cells were plated on laminin-coated coverslips for 24 hours, fixed and processed for indirect immunofluorescence using a vinculin antibody and Texas-Red-labeled secondary antibody. Micrographs depict cells with low GFP-Wrch-1 expression level. Punctate staining in the center of the cell that does not correspond to focal adhesions is indicated with an asterisk. Bar, 10 μm. Ya-yu Chuang et al. J Cell Sci 2007;120:1927-1934 © The Company of Biologists Limited 2007