Fine mapping of SRT1. Fine mapping of SRT1. To fine map the SRT1 locus, we compared the sequencing data and developed a set of InDel markers in the 5 Mb.

Slides:

Advertisements

Similar presentations

Identification of markers linked to Selenium tolerance genes

Advertisements

Linkage and Gene Mapping. Mendel’s Laws: Chromosomes Locus = physical location of a gene on a chromosome Homologous pairs of chromosomes often contain.

Gene mapping – first lecture. 13_01.jpg 13_02.jpg.

Positional Cloning LOD Sib pairs Chromosome Region Association Study Genetics Genomics Physical Mapping/ Sequencing Candidate Gene Selection/ Polymorphism.

Announcements: Proposal resubmission deadline 4/23 (Thursday).

10cM - Linkage Mapping Set v2 ABI Median intermarker distance: 4.7 Mb Mean intermarker distance: 5.6 Mb Mean genetic gap distance: 8.9 cM Average Heterozygosity.

What do we already know ? The rice disease resistance gene Pi-ta Genetically mapped to chromosome 12 Rybka et al. (1997). It has also been sequenced Bryan.

Physical Map and Organization of Arabidopsis thaliana Chromosome 4

Chen_SupMat 5 – Figure S3. Distribution of private alleles in B

Copyright © 2000 American Medical Association. All rights reserved.

Physical map of a human chromosome

Copyright © 2001 American Medical Association. All rights reserved.

BAC-Based Physical Map of the Rice Genome.

GWLSs in a family with hereditary VUR

Genome organization and Bioinformatics

Der(22) Syndrome and Velo-Cardio-Facial Syndrome/DiGeorge Syndrome Share a 1.5- Mb Region of Overlap on Chromosome 22q11 B. Funke, L. Edelmann, N. McCain,

EpiQTL mapping of glucosinolate mean and CV

Lecture 9 Genome Mapping By Ms. Shumaila Azam

An Autosomal Dominant Thrombocytopenia Gene Maps to Chromosomal Region 10p Anna Savoia, Maria Del Vecchio, Antonio Totaro, Silverio Perrotta, Giovanni.

Linkage Disequilibrium Mapping of Schizophrenia Susceptibility to the CAPON Region of Chromosome 1q22 Linda M. Brzustowicz, Jaime Simone, Paria Mohseni,

Significant genes at the 1% nominal level either in Europe, Asia or both, present in the significant pathways obtained from the nSL (linkage disequilibrium)

A Combined Linkage-Physical Map of the Human Genome

A. Vanita, Jai Rup Singh, Virinder K

The Novel Genetic Disorder Microhydranencephaly Maps to Chromosome 16p

Molecular Cytogenetic Evidence for a Common Breakpoint in the Largest Inverted Duplications of Chromosome 15 A.E. Wandstrat, J. Leana-Cox, L. Jenkins,

Caroline Durrant, Krina T. Zondervan, Lon R

SNP calls and map positions on linkage group 7D for 19 Affymetrix Axiom IStraw90 probes comprising the four most abundant haplotypes in the FaRPc2 QTL.

The Gene for Severe Combined Immunodeficiency Disease in Athabascan-Speaking Native Americans Is Located on Chromosome 10p Lanying Li, Dennis Drayna,

A Gene Mutated in Nephronophthisis and Retinitis Pigmentosa Encodes a Novel Protein, Nephroretinin, Conserved in Evolution Edgar Otto, Julia Hoefele,

Elizabeth Theusch, Analabha Basu, Jane Gitschier

Evidence for a Nonallelic Heterogeneity of Epidermodysplasia Verruciformis with Two Susceptibility Loci Mapped to Chromosome Regions 2p21–p24 and 17q25

Genetic Investigations of Kidney Disease: Core Curriculum 2013

John D. Rioux, Valerie A. Stone, Mark J

Gene mapping March 3, 2017.

Airong Li, Sonia Davila, Laszlo Furu, Qi Qian, Xin Tian, Patrick S

Disruption of Contactin 4 (CNTN4) Results in Developmental Delay and Other Features of 3p Deletion Syndrome Thomas Fernandez, Thomas Morgan, Nicole Davis,

Hal M. Hoffman, Fred A. Wright, David H. Broide, Alan A

Attention Deficit Hyperactivity Disorder: Fine Mapping Supports Linkage to 5p13, 6q12, 16p13, and 17p11 Matthew N. Ogdie, Simon E. Fisher, May Yang,

A, genomic copy number profiles of chromosome 8 with array CGH in SUM-44, -52, and A, genomic copy number profiles of chromosome 8 with array CGH.

Phenotype of S-Cp1-1 and mapping of the Cp1 locus.

sac mutants are hypersensitive to IR

Homozygosity and Linkage-Disequilibrium Mapping of the Syndrome of Congenital Hypoparathyroidism, Growth and Mental Retardation, and Dysmorphism to a.

Heat map of additive effects for PCs QTL

Mapping rates of different transcript sets to the P

MetaPhase clustering results on the M-Y draft metagenome assembly.

Identifying Novel Genes for Atherosclerosis through Mouse-Human Comparative Genetics Xiaosong Wang, Naoki Ishimori, Ron Korstanje, Jarod Rollins, Beverly.

A diagram summarizing the evolutionary history of the distal regions of chromosome arms 4L and 5L of Triticeae diploids. A diagram summarizing the evolutionary.

Linkage Analysis in a Large Brazilian Family with van der Woude Syndrome Suggests the Existence of a Susceptibility Locus for Cleft Palate at 17p

Mean C-to-U editing ratios for most editing sites map to a region on chromosome 6 at 122 Mb. (A) Genome scan of mean C-to-U editing for 70 editing sites.

The first two principal components for the islet gene expression data for the 181 microarray probes that map to the chromosome 6 trans-eQTL hotspot with.

Flowering-time QTL in crosses of Lz-0 with Ler and Col.

Genetic dissection of the effect of chromosomes 2 and 3 on progeny number from D. virilis–D. americana crosses. Genetic dissection of the effect of chromosomes.

S. Fernandes, S. Paracchini, L. H. Meyer, G. Floridia, C

Der(22) Syndrome and Velo-Cardio-Facial Syndrome/DiGeorge Syndrome Share a 1.5- Mb Region of Overlap on Chromosome 22q11 B. Funke, L. Edelmann, N. McCain,

Genome Scan of Human Systemic Lupus Erythematosus by Regression Modeling: Evidence of Linkage and Epistasis at 4p C. Gray-McGuire, K.L. Moser,

Identification, by Homozygosity Mapping, of a Novel Locus for Autosomal Recessive Congenital Ichthyosis on Chromosome 17p, and Evidence for Further Genetic.

Genomic structure of LTBP-4 around the 3rd 8-Cys repeat.

A Gene for an Autosomal Dominant Scleroatrophic Syndrome Predisposing to Skin Cancer (Huriez Syndrome) Maps to Chromosome 4q23 Young-Ae Lee, Howard P.

Whole-chromosome view of gene density, inverse environmental variation, inverse total variation, and open chromatin signature. Whole-chromosome view of.

The MEG3 promoter and enhancer interact with other putative enhancers within the DLK1-MEG3–imprinted region. The MEG3 promoter and enhancer interact with.

Neighbor-joining tree of the 262 S

Comparative mapping of LG1 of the white grouper (center) and its syntenic LGs EBR13 of the kelp grouper (right), and ECO8 of the orange-spotted grouper.

A New Familial Amyotrophic Lateral Sclerosis Locus on Chromosome 16q12

Information on sequenced Q. lobata adult #786.

Identification of a ufo1 Candidate Gene from the Mapping Region.

Mapping of srt1 by BSA-seq.

Genome-wide Scan and Fine-Mapping Linkage Study of Androgenetic Alopecia Reveals a Locus on Chromosome 3q26 Axel M. Hillmer, Antonia Flaquer, Sandra.

Volume 23, Issue 10, Pages (May 2013)

Sequence Homology between 4qter and 10qter Loci Facilitates the Instability of Subtelomeric KpnI Repeat Units Implicated in Facioscapulohumeral Muscular.

Bruce Rannala, Jeff P. Reeve The American Journal of Human Genetics

Presentation transcript:

Fine mapping of SRT1. Fine mapping of SRT1. To fine map the SRT1 locus, we compared the sequencing data and developed a set of InDel markers in the 5 Mb region of chromosome 4 identified by BSA-seq. Linkage analysis using these molecular markers first placed SRT1 on a short genomic region between ST_8 and ST_23. Further linkage analysis using markers developed in this region delimited SRT1 within a region of ∼231 kb between ST_18 and STSNP_3, with tight linkage to ST_5. Genetic distances in cM between two neighboring markers are indicated on left side of chromosome. Fredrick Mwamburi Mjomba et al. G3 2016;6:2013-2021 ©2016 by Genetics Society of America