Volume 128, Issue 4, Pages (April 2005)

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(A) Percentage of patients achieving remission or response at week 12 or 24 after initiating ova therapy. (A) Percentage of patients achieving remission.

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Volume 128, Issue 4, Pages 825-832 (April 2005) Trichuris suis therapy for active ulcerative colitis: A randomized controlled trial Robert W. Summers, David E. Elliott, Joseph F. Urban, Robin A. Thompson, Joel V. Weinstock Gastroenterology Volume 128, Issue 4, Pages 825-832 (April 2005) DOI: 10.1053/j.gastro.2005.01.005 Copyright © 2005 American Gastroenterological Association Terms and Conditions

Figure 1 Flow diagram of study participants. COPD, chronic obstructive pulmonary disease. Gastroenterology 2005 128, 825-832DOI: (10.1053/j.gastro.2005.01.005) Copyright © 2005 American Gastroenterological Association Terms and Conditions

Figure 2 Percentage of patients achieving response. Response was defined as a decrease in UCDAI of ≥4 at week 12. Values for the intention-to-treat analysis are based on all 54 patients enrolled, whereas those for the per-protocol analysis are based on 52 patients. One patient withdrew from each of the placebo- and ova-treatment groups. Gastroenterology 2005 128, 825-832DOI: (10.1053/j.gastro.2005.01.005) Copyright © 2005 American Gastroenterological Association Terms and Conditions

Figure 3 Percentage of patients achieving UCDAI 0–1 (not significant). Gastroenterology 2005 128, 825-832DOI: (10.1053/j.gastro.2005.01.005) Copyright © 2005 American Gastroenterological Association Terms and Conditions

Figure 4 UCDAI scores for stool frequency, stool blood, mucosal appearance, or overall assessment at baseline and week 12. Ova-treated subjects had significant mean improvements in all parameters. Placebo-treated subjects showed improvement only in stool frequency. Analysis was intention to treat. Gastroenterology 2005 128, 825-832DOI: (10.1053/j.gastro.2005.01.005) Copyright © 2005 American Gastroenterological Association Terms and Conditions

Figure 5 Simple Index for placebo-treated (•) and ova-treated patients (□). Compared with baseline (time 0), there was a progressive decrease in the Simple Index in the ova-treated patients. *P = .032 at week 6; P = .003 at week 8; P = .014 at week 10; P < .0001 at week 12. There was no significant change over time in the Simple Index in the placebo group. Gastroenterology 2005 128, 825-832DOI: (10.1053/j.gastro.2005.01.005) Copyright © 2005 American Gastroenterological Association Terms and Conditions