A and B: Intracellular cAMP levels and lipolysis in adipocytes from chow-fed and HFD-fed mice. A and B: Intracellular cAMP levels and lipolysis in adipocytes.

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A and B: Intracellular cAMP levels and lipolysis in adipocytes from chow-fed and HFD-fed mice. A and B: Intracellular cAMP levels and lipolysis in adipocytes from chow-fed and HFD-fed mice. A: Levels of cAMP in chow or HFD subcutaneous adipocytes during 30-min incubations in the presence of FSK/IBMX, epinephrine (EPI), or CL. B: Lipolysis measured as glycerol release in chow and HFD adipocytes (30 min). Data in A and B are from six chow-fed and six HFD-fed animals. *P < 0.05; **P < 0.01; ***P < 0.001. Ali M. Komai et al. Diabetes 2016;65:3301-3313 ©2016 by American Diabetes Association