Figure. Factors that can influence the severity of RV infections and the risk of RV-induced exacerbations of asthma. In children and adults with asthma,

Slides:

Advertisements

Similar presentations

Supplemental Figure 1 A No. at risk T T T

Advertisements

Interactions between viral infections and allergy in exacerbating asthma.

Sensitization to Allergen Requires sufficient exposure (concentration and time) Requires genetic predisposition.

CATEGORY: IMMUNE DEVELOPMENT Neonatal Immunology John Tregoning, St George’s University of London, UK Introduction Like many other systems in the body,

Immunology Unit Department of Pathology King Saud University

Food Protein-Induced Non-Immunoglobulin E-Mediated Allergic Colitis in Infants and Older Children: What Cytokines Are Involved? Int Arch Allergy Immunol.

The Relationship Between a Specific IgE Level and Asthma Outcomes: Results from the National Health and Nutrition Examination Survey Whitney.

Figure. Changes in the proportion of AD and exclusive breast-feeding in children at 1 to 3 years of age (KNHANES-IV and V, ). This survey was.

Fig. 2. Comparison of the Th1/Th2 ratio and the percentages of Th1 and Th2 cells between normal and allergic individuals. (A) The Th1/Th2 ratio observed.

Fig. 5. Effects of siRNA against TLR2 and TLR5 on the expression of thymic stromal lymphopoietin (TSLP) from nasal polyp fibroblasts. Fibroblasts were.

THE WHEEZY INFANT: WILL HE BECOME AN ASTHMATIC CHILD?

Fig. 2. IgE Immunoblotting analysis with pooled sera of egg-allergic patients. (A) shows an immunoblot result using native serum. (B) is a immunoblot result.

Allergy Testing in Children

IL-17–producing T cells in lung immunity and inflammation

The role of viruses in acute exacerbations of asthma

Eosinophilic Esophagitis: Is It All Allergies?

Allergic Rhinitis and Its Impact on Asthma

Peter J. Barnes, FMedSci, FRS

Atopic dermatitis and the atopic march

Is 9 more than 2 also in allergic airway inflammation?

Frederick J. Rubner, MD, Daniel J. Jackson, MD, Michael D

Two different pathways lead to eosinophilic airway inflammation in asthma. Two different pathways lead to eosinophilic airway inflammation in asthma. In.

Association of rhinovirus species with common cold and asthma symptoms and bacterial pathogens Hiba Bashir, MD, Kristine Grindle, BS, Rose Vrtis, BS,

The changing face of asthma and its relation with microbes

Detection of pathogenic bacteria during rhinovirus infection is associated with increased respiratory symptoms and asthma exacerbations Kirsten M. Kloepfer,

The Relationship Between a Specific IgE Level and Asthma Outcomes: Results from the National Health and Nutrition Examination Survey Whitney.

Exploiting Old Pathogens to Create New Therapeutics

Diagnosis, Evaluation, and Therapy for Severe Refractory Eosinophilic Asthma.

Daniel J. Jackson, MD, James E. Gern, MD, Robert F. Lemanske, MD

Forest plot showing the number of adults (at the top) and children (lower down) who were admitted to hospital after treatment in the emergency department.

Intranasal live-attenuated influenza vaccine (LAIV) is unlikely to cause egg-mediated allergic reactions in egg-allergic children Paul J. Turner, FRACP,

Rhinovirus (RV) infection induces caspase-1 expression in bronchial epithelial cells in asthma. Rhinovirus (RV) infection induces caspase-1 expression.

Infection with a respiratory virus before hematopoietic cell transplantation is associated with alloimmune-mediated lung syndromes Birgitta Versluys,

The changing face of asthma and its relation with microbes

6. Asthma Journal of Allergy and Clinical Immunology

The role of the T cell in asthma

Fig. 3. Activation of MMCs and CTMCs after stimulation through FcεRI

The role of rhinovirus in asthma exacerbations

Fig. 4. Immunomodulation by TolDCs

Immunology Unit Department of Pathology King Saud University

Fig. 2. Sera IgE reactivity patterns and the frequency of reactivity to raw and cooked shrimp extracts by Western blot. (A, C) All sera were diluted at.

Fig. 3. Reporter assay for the RS-ATL8 reporter cell line against shrimp extracts (A, B) RS-ATL8 cells were sensitized overnight with diluted pooled sera.

Fig. 5. Silencing of TAB2 mimics the effects of miR-155-5p on BSMCs

Association of IL-33 with asthma during RSV infection.

Fig. 2. Effect of capsazepine and TRPV1 siRNA on total/differential cell counts in BAL fluid. Mice were sacrificed after measurement of AHR, and BAL was.

Fig. 6. Mucus analysis of lungs from allergic and tolerized mice

Fig. 2. GCE induces allergic inflammation in the mouse model of asthma

Fig. 2. Binding of specific IgE to D20110 and S47W

Viral infections in allergy and immunology: How allergic inflammation influences viral infections and illness Michael R. Edwards, PhD, Katherine Strong,

Fig. 4. Levels of serum total IgE and IgE concentrations secreted into supernatants of the PBMCs cultured for 3, 5, and 7 days the AR patients and the.

Fig. 2. Putative mechanisms of oral tolerance induction in the gut

Deficient antiviral immune responses in childhood: Distinct roles of atopy and asthma Simonetta Baraldo, PhD, Marco Contoli, MD, PhD, Erica Bazzan, PhD,

Fig. 1. Treatment with IL-13 induces proliferation and migration of BSMCs. (A) MTT assay was performed to evaluate the effects of IL-13 on the proliferation.

*P < 0.01; †P < The experiments were repeated 5 times.

*P < 0.01 and †P < The experiments were repeated 6 times.

Supplementary Fig. S1. A summary of the suggested mechanism underlying asthma. PAR2, activated by a protease-containing allergen, induces the generation.

Tuomas Jartti, MD, James E. Gern, MD

Salmeterol attenuates chemotactic responses in rhinovirus-induced exacerbation of allergic airways disease by modulating protein phosphatase 2A Luke.

Effect of the presence of aetiological factors (bacterial or viral infection, or eosinophilic inflammation) at stable visits on the odds of experiencing.

*P < 0.05; †P < The experiments were repeated 5 times.

Fig. 4. The expression of TRAF6 in the PBMCs of the AR children after a 3-month SIT treatment. (A) Representative Western blot analysis of TRAF6 in the.

Fig. 1. Levels of Th2 and Th17 cytokines in HDM-induced mouse model of asthma. (A) The design of the HDM-induced mouse model of asthma. (B) The numbers.

Getting Acquainted with CCR3

The Editors’ Choice Journal of Allergy and Clinical Immunology

Supplementary Fig. S5. Protein profiles in the DIA set

Supplementary Fig. S2. Profile plot of the proteomics analysis

Fig. 2. Chart summarizing the vital signs of the patient with anaphylaxis. Arrows indicate drug administrations: the first narrow arrow, 450 mg of pentothal.

Fig. 1. Protein analysis of the German cockroach extracts

Fig. 3. Structural equation modeling to estimate relationships among K-UCT and UAS7/CU-QoL/salivary cortisone levels. The K-UCT was found to be a significant.

Schematic diagram of the potential cellular effects of interleukin (IL)-4/IL-13 on inflammatory and structural cells in asthma. Schematic diagram of the.

Presentation transcript:

Figure. Factors that can influence the severity of RV infections and the risk of RV-induced exacerbations of asthma. In children and adults with asthma, the severity of RV infection is positively related to the probability of exacerbation. Factors that increase the likelihood of more severe RV illnesses and exacerbations of asthma include the species of RV, the presence of bacterial pathogens in the airway, allergic inflammation, and polymorphisms in CDHR3 and the 17q21 region of the genome. RV, rhinovirus; CDHR3, cadherin-related protein-3; IgE, immunoglobulin E; Eos, eosinophils. Figure. Factors that can influence the severity of RV infections and the risk of RV-induced exacerbations of asthma. In children and adults with asthma, the severity of RV infection is positively related to the probability of exacerbation. Factors that increase the likelihood of more severe RV illnesses and exacerbations of asthma include the species of RV, the presence… Allergy Asthma Immunol Res. 2018 Jan;10(1):12-17. https://doi.org/10.4168/aair.2018.10.1.12