Analgesic effectiveness of caudal levobupivacaine and ketamine

Slides:

Advertisements

Similar presentations

Reduction in mortality after epidural anaesthesia and analgesia in patients undergoing rectal but not colonic cancer surgery: a retrospective analysis.

Advertisements

C Dualé, C Frey, F Bolandard, A Barrière, P Schoeffler

AnestAssist British Journal of Anaesthesia

Effect of haemodilution, acidosis, and hypothermia on the activity of recombinant factor VIIa (NovoSeven®) D. Viuff, B. Lauritzen, A.E. Pusateri, S.

Rectal and parenteral paracetamol, and paracetamol in combination with NSAIDs, for postoperative analgesia J. Rømsing, S. Møiniche, J.B. Dahl British.

Randomized controlled trial of duration of analgesia following intravenous or rectal acetaminophen after adenotonsillectomy in children F. Capici, P.M.

Comparison of the performance of SAPS II, SAPS 3, APACHE II, and their customized prognostic models in a surgical intensive care unit Y. Sakr, C. Krauss,

Antiemetic and analgesic-sparing effects of diphenhydramine added to morphine intravenous patient-controlled analgesia T.-F. Lin, Y.-C. Yeh, Y.-H. Yen,

Parkinson's disease and anaesthesia

A comparison of the analgesic efficacy and side-effects of paravertebral vs epidural blockade for thoracotomy—a systematic review and meta-analysis of.

Development and longitudinal validation of the overall benefit of analgesia score: a simple multi-dimensional quality assessment instrument N Lehmann,

Spinal anaesthesia for elective surgery: a comparison of hyperbaric solutions of racemic bupivacaine, levobupivacaine, and ropivacaine J.F. Luck, P.D.W.

M.S. Evans, C. Lysakowski, M.R. Tramèr British Journal of Anaesthesia

Changes in glomerular filtration rate after cardiac surgery with cardiopulmonary bypass in patients with mild preoperative renal dysfunction B.G. Loef,

A different use of visual analytic techniques in anaesthetics

Multicentre evaluation of the adenosine agonist GR79236X in patients with dental pain after third molar extraction J.R. Sneyd, J.A. Langton, L.G. Allan,

R.S. Bondok, A.M. Abd El-Hady British Journal of Anaesthesia

R.J.Ni Mhuircheartaigh, R.A. Moore, H.J. McQuay

T. Ledowski, J. Burke, J. Hruby British Journal of Anaesthesia

Epidural infusion or combined femoral and sciatic nerve blocks as perioperative analgesia for knee arthroplasty† Davies A.F. , Segar E.P. , Murdoch J.

Postoperative pain after hip fracture is procedure specific

Intrathecal ropivacaine for total hip arthroplasty: double-blind comparative study with isobaric 7.5 mg ml−1 and 10 mg ml−1 solutions D.A. McNamee, L.

Evaluation of a single preoperative dose of pregabalin for attenuation of postoperative pain after laparoscopic cholecystectomy A. Agarwal, S. Gautam,

SB366791, a TRPV1 antagonist, potentiates analgesic effects of systemic morphine in a murine model of bone cancer pain† Y. Niiyama, T. Kawamata, J. Yamamoto,

A. Vasudevan, C.E. Snowman, S. Sundar, T.W. Sarge, P.E. Hess

Spinal anaesthesia: comparison of plain ropivacaine 5 mg ml−1 with bupivacaine 5 mg ml−1 for major orthopaedic surgery D.A. McNamee, A.M. McClelland,

Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day- case gynaecological laparoscopic surgery R. Jokela, J. Ahonen, M.

Acute pain: combination treatments and how we measure their efficacy

Effect of postoperative analgesia on surgical outcome

Efficacy of intravenous magnesium in neuropathic pain

Does regional anaesthesia improve outcome?

Block of the sacral segments in lumbar epidural anaesthesia

Psychology of pain British Journal of Anaesthesia

K.J. Chin British Journal of Anaesthesia

Psoas compartment block for lower extremity surgery: a meta-analysis

Effects of magnesium sulphate on intraoperative anaesthetic requirements and postoperative analgesia in gynaecology patients receiving total intravenous.

Epidural analgesia compared with peripheral nerve blockade after major knee surgery: a systematic review and meta-analysis of randomized trials S.J.

I.V. paracetamol as an adjunct to patient-controlled epidural analgesia with levobupivacaine and fentanyl in labour: a randomized controlled study K.

Effects of intraoperative i. v. acetaminophen vs i. m

Comparative study of topical anaesthesia with lidocaine 2% vs levobupivacaine 0.75% in cataract surgery S.A. Fernández, E. Dios, J.C. Diz British Journal.

H. Tønnesen, P.R. Nielsen, J.B. Lauritzen, A.M. Møller

A. M. El-Hennawy, A. M. Abd-Elwahab, A. M. Abd-Elmaksoud, H. S

G. Park, M. Lane, S. Rogers, P. Bassett British Journal of Anaesthesia

Perioperative administration of fibrinogen does not increase adverse cardiac and thromboembolic events after cardiac surgery J. Fassl, G. Lurati Buse,

Assessing fitness for surgery: a comparison of questionnaire, incremental shuttle walk, and cardiopulmonary exercise testing in general surgical patients†

Pharmacogenetics of codeine metabolism in an urban population of children and its implications for analgesic reliability D.G. Williams, A. Patel, R.F.

Caudal dexmedetomidine combined with bupivacaine inhibit the response to hernial sac traction in children undergoing inguinal hernia repair Q. Xiang,

Is age a predictor of mortality in a UK medical high dependency unit?

H Viitanen, P Annila British Journal of Anaesthesia

Effectiveness of continuous wound infusion of 0

GlideScope® video laryngoscope: a randomized clinical trial in 203 paediatric patients† J.-T. Kim, H.-S. Na, J.-Y. Bae, D.-W. Kim, H.-S. Kim, C.S. Kim,

G.J. Mar, M.J. Barrington, B.R. McGuirk British Journal of Anaesthesia

Differential impacts of modes of anaesthesia on the risk of stroke among preeclamptic women who undergo Caesarean delivery: a population-based study

Parecoxib for analgesia after craniotomy

Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy J.-Y. Hong, S.W. Han, W.O.

The preoperative administration of ketoprofen improves analgesia after laparoscopic cholecystectomy in comparison with propacetamol or postoperative ketoprofen

Acute kidney injury following orthotopic liver transplantation: incidence, risk factors, and effects on patient and graft outcomes I.A. Hilmi, D. Damian,

Epidural analgesia with 0. 15% ropivacaine plus sufentanil 0

Development and validation of a preoperative scoring system to predict 30 day mortality in patients undergoing hip fracture surgery M.J. Maxwell, C.G.

C. Verghese, B. Ramaswamy British Journal of Anaesthesia

J. Carlisle, M. Swart, E.J.C. Dawe, M. Chadwick

T. -F. Lin, Y. -C. Yeh, F. -S. Lin, Y. -P. Wang, C. -J. Lin, W. -Z

Caudal bupivacaine supplemented with caudal or intravenous clonidine in children undergoing hypospadias repair: a double-blind study T.G. Hansen, S.W.

I.V. ropivacaine compared with lidocaine for the treatment of tinnitus

Effects of magnesium sulphate on intraoperative neuromuscular blocking agent requirements and postoperative analgesia in children with cerebral palsy

Association of opioid requirement and cancer pain with survival in advanced non-small cell lung cancer D. Zylla, M.A. Kuskowski, K. Gupta, P. Gupta

M. J. Sheen, S. -T. Ho, C. -H. Lee, Y. -C. Tsung, F. -L. Chang, S. -T

Epinephrine and clonidine do not improve intrathecal sufentanil analgesia after total hip replacement† R. Fournier, E. Van Gessel, A. Weber, Z. Gamulin

Analgesia for day-case surgery†

Nottingham Hip Fracture Score as a predictor of one year mortality in patients undergoing surgical repair of fractured neck of femur M.D. Wiles, C.G.

Presentation transcript:

Analgesic effectiveness of caudal levobupivacaine and ketamine B.G. Locatelli, G. Frawley, A. Spotti, P. Ingelmo, S. Kaplanian, B. Rossi, L. Monia, V. Sonzogni British Journal of Anaesthesia Volume 100, Issue 5, Pages 701-706 (May 2008) DOI: 10.1093/bja/aen048 Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

Fig 1 Incidence of postoperative pain and distress with caudal solutions of levobupivacaine and ketamine. CHIPPS score of ≤3 described mild or no pain, 4–6 moderate, and ≥7 severe pain. A CHIPPS score of ≥4 at wakeup or up to 360 min after caudal block was treated with supplemental analgesia. British Journal of Anaesthesia 2008 100, 701-706DOI: (10.1093/bja/aen048) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

Fig 2 Results of Kaplan–Meier survival analysis are displayed as survival curves for the three caudal solutions. Mantel-Cox (log-rank) test was used to compare the rate of requirement for additional analgesia in the study with the rate of expected requirements for additional analgesia if all groups had received equally effective caudal analgesia. Group 1 (0.15% levobupivacaine with 0.5 mg kg−1 ketamine) was significantly different (P=0.05) to Group 2 (0.175% levobupivacaine with 0.5 mg kg−1 ketamine) but not Group 3 (0.2% levobupivacaine) (P=0.27). There was no significant difference between Group 2 and Group 3 (P=0.15). British Journal of Anaesthesia 2008 100, 701-706DOI: (10.1093/bja/aen048) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

Fig 3 Incidence of residual motor block with caudal solutions of levobupivacaine or ketamine levobupivacaine. Residual motor block is defined as Bromage score of greater than one at wakeup or up to 180 min after caudal block. British Journal of Anaesthesia 2008 100, 701-706DOI: (10.1093/bja/aen048) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions