A woman with spontaneous premature ovarian failure gives birth to a child with fragile X syndrome  Emily C. Corrigan, B.S., Margarita J. Raygada, M.Sc., Ph.D., Vien H. Vanderhoof, C.R.N.P., Lawrence M. Nelson, M.D.  Fertility and Sterility  Volume 84, Issue 5, Pages 1508.e5-1508.e8 (November 2005) DOI: 10.1016/j.fertnstert.2005.06.019 Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions

FIGURE 1 Pedigree. The patient is indicated with an arrowhead. Current ages or ages at the time of death are indicated. All known family members who have tested positive for an abnormality in the FMR1 gene are shown. The dot indicates tested negative for FMR1 gene abnormality. “Early SAB” indicates a spontaneous abortion or miscarriage in the first trimester. “Menstrual Irregularity” means the person possibly had premature ovarian failure but was never formally diagnosed. The ethnic heritage and countries of origin of the maternal and paternal families are shown. Fertility and Sterility 2005 84, 1508.e5-1508.e8DOI: (10.1016/j.fertnstert.2005.06.019) Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions