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Nat. Rev. Nephrol. doi:10.1038/nrneph.2017.187 Figure 3 Adverse pregnancy outcomes according to chronic kidney disease stage Figure 3 | Adverse pregnancy outcomes according to chronic kidney disease stage. Two cohort studies60,78 show that worsening of renal function (as assessed by chronic kidney disease (CKD) stage) correlates with a consistent increment in several pregnancy complications: preterm delivery; pre-eclampsia; neonatal intensive care unit (NICU) admission; loss of residual maternal renal function; and small-for-gestational-age (SGA) infants (parts a and b). Variation of absolute rates of adverse pregnancy outcomes between the studies could be due to differences in cohort size, the use of estimated glomerular filtration rate (eGFR) in pregnancy and different thresholds for both iatrogenic preterm delivery and NICU admission. In addition, pre-eclampsia was excluded from the control group in one study78. RRT, renal replacement therapy. Wiles, K. S. et al. (2018) Reproductive health and pregnancy in women with chronic kidney disease Nat. Rev. Nephrol. doi:10.1038/nrneph.2017.187