Spontaneous pregnancy in a patient who was homozygous for the Q106R mutation in the gonadotropin-releasing hormone receptor gene Didier Dewailly, M.D.,

Slides:

Advertisements

Similar presentations

Prediction of the effects of gonadotropin-releasing hormone agonist therapy in uterine leiomyoma by T1 contrast-enhanced magnetic resonance imaging sequences

Advertisements

Leptin receptor variant in women with polycystic ovary syndrome

Is the type of gonadotropin-releasing hormone suppression protocol for ovarian hyperstimulation associated with ectopic pregnancy in fresh autologous.

Quality of life and psychosocial and physical well-being among 1,023 women during their first assisted reproductive technology treatment: secondary outcome.

Challenges of genetic counseling in patients with autosomal dominant diseases, such as the hyper-IgE syndrome (STAT3-HIES) Benedikt D. Spielberger, Cristina.

Is the effect of premature elevated progesterone augmented by human chorionic gonadotropin versus gonadotropin-releasing hormone agonist trigger? Matthew.

PROGINS receptor gene polymorphism is associated with endometriosis

Novel homozygous nonsense mutations in the luteinizing hormone receptor (LHCGR) gene associated with 46,XY primary amenorrhea Imen Ben Hadj Hmida, Ph.D.,

Does Previous Salpingectomy Improve Implantation and Pregnancy Rates in Patients with Severe Tubal Factor Infertility who are Undergoing In Vitro Fertilization?

Pituitary desensitization to gonadotropin-releasing hormone increases abdominal adiposity in hyperandrogenic anovulatory women Daniel A Dumesic, M.D.,

Impact of endogenous luteinizing hormone serum levels on progesterone elevation on the day of human chorionic gonadotropin administration Jean-noêl Hugues,

Next generation sequencing in women affected by nonsyndromic premature ovarian failure displays new potential causative genes and mutations Dora Janeth.

Christine Jablonski, M. D. , Marco Alifano, M. D

Can pregnancy rate be improved in gonadotropin-releasing hormone (GnRH) antagonist cycles by administering GnRH agonist before oocyte retrieval? A prospective,

A novel mutation c.118delA in exon 1 of the androgen receptor gene resulting in complete androgen insensitivity syndrome within a large family Karel.

Serum levels of inhibins are differentially altered in patients with polycystic ovary syndrome: effects of being overweight and relevance to hyperandrogenism

Heterozygous variant at nucleotide position A>T in exon 6A cystic fibrosis transmembrane conductance regulator gene induces 852del22 mutation false-positivity.

Obesity and serum luteinizing hormone level have an independent and opposite effect on the serum inhibin B level in patients with polycystic ovary syndrome

A randomized controlled study comparing the endocrine effects of pulsatile intravenous gonadotropin-releasing hormone after gonadotropin-releasing hormone.

Craig A. H Richard, Ph. D. , Carolyn J Kubik, M. D

CYP19 gene: a genetic modifier of polycystic ovary syndrome phenotype

Effect of short-term hormone therapy on oxidative stress and endothelial function in African American and Caucasian postmenopausal women Raymond W Ke,

Endometrial cyst of the liver: case report and review

Christine L Cook, M. D. , Yong Siow, Ph. D. , Susan Taylor, B. A

Effect of prolonged gonadotropin-releasing hormone agonist therapy on the outcome of in vitro fertilization-embryo transfer in patients with endometriosis

Microdose follicular phase gonadotropin-releasing hormone agonists (GnRH-a) compared with luteal phase GnRH-a for ovarian stimulation at in vitro fertilization5

The first successful paternity through in vitro fertilization–intracytoplasmic sperm injection with a man homozygous for the 5α-reductase-2 gene mutation

M. Dieterich, M. Bolz, T. Reimer, S. Costagliola, B. Gerber

Adrenocortical hyperresponsivity to adrenocorticotropic hormone: a mechanism favoring the normal production of cortisol in 21-hydroxylase-deficient nonclassic.

Laurent Gouya Journal of Investigative Dermatology

Robert F. Casper, M.D. Fertility and Sterility

Interleukin-1β regulation of gonadotropin-releasing hormone messenger ribonucleic acid in cultured human endometrial stromal cells Hong-Yuan Huang, M.D.,

Ultrashort flare gonadotropin-releasing hormone (GnRH) agonist/GnRH antagonist protocol: a valuable tool in the armamentarium of ovulation induction for.

Mutational analysis of androgen receptor gene in four Chinese patients with male pseudohermaphroditism Xueyan Wu, M.D., Qi Zhou, M.Sc., Jiangfeng Mao,

No evidence of the inactivating mutation (C566T) in the follicle-stimulating hormone receptor gene in Brazilian women with premature ovarian failure

Familial gonadotropin-releasing hormone resistance and hypogonadotropic hypogonadism in a family with multiple affected individuals Lawrence C Layman,

Bo Yu, M.D., Jane Ruman, M.D., Gregory Christman, M.D.

Pretreatment with estrogen does not affect IVF-ICSI cycle outcome compared with no pretreatment in GnRH antagonist protocol: a prospective randomized.

Follicle-stimulating hormone or human menopausal gonadotropin for ovarian stimulation in in vitro fertilization cycles: a meta-analysis Rina Agrawal,

Gonadotropin-releasing hormone antagonist use is associated with increased pregnancy rates in ovulation induction–intrauterine insemination to in vitro.

New Developments in the Medical Management of Prostate Cancer

Changes in cytokine levels of patients with ovarian endometriosis after treatment with gonadotropin-releasing hormone analogue, ultrasound-guided drainage,

Should gamete donors be tested for spinal muscular atrophy?

Assessment of luteinizing hormone level in the gonadotropin-releasing hormone antagonist protocol Georg Griesinger, M.D., Anja Dawson, M.D., Askan Schultze-Mosgau,

Preimplantation genetic diagnosis for Zellweger syndrome

Aaron K. Styer, M. D. , Diane L. Wright, Ph. D. , H. C. L. D. , Anne M

Prediction of the effects of gonadotropin-releasing hormone agonist therapy in uterine leiomyoma by T1 contrast-enhanced magnetic resonance imaging sequences

Effectiveness of highly purified human menopausal gonadotropin vs

Regulation of assisted reproductive technologies in the United States

Human myometrium and leiomyomas express gonadotropin-releasing hormone 2 and gonadotropin-releasing hormone 2 receptor Jason D. Parker, D.O., Minnie.

Effect of endometriosis on in vitro fertilization

Pregnancy outcome in infertile patients with polycystic ovary syndrome who were treated with metformin Samuel S. Thatcher, M.D., Ph.D., Elizabeth M.

Effect of gonadotropin-releasing-hormone-induced hypogonadism on insulin action as assessed by euglycemic clamp studies in men Subodhsingh Chauhan, M.D.,

Ellen Pfendner, Jouni Uitto Journal of Investigative Dermatology

Administration of gonadotropin-releasing hormone antagonist from day 1 of stimulation in in vitro fertilization Efstratios M Kolibianakis, M.D., Kostas.

Marcia A Ellison, PhD, Janet E Hall, MD Fertility and Sterility

Cost-effectiveness comparison between pituitary down-regulation with a gonadotropin- releasing hormone agonist short regimen on alternate days and an antagonist.

The luteinizing hormone β-subunit exon 3 (Gly102Ser) gene mutation is rare in Korean women with endometriosis and polycystic ovary syndrome Nam Keun.

Effectiveness of short-term administration of tibolone plus gonadotropin-releasing hormone analogue on the surgical outcome of laparoscopic myomectomy

Concomitant treatment of severe uterine adenomyosis in a premenopausal woman with an aromatase inhibitor and a gonadotropin-releasing hormone agonist

Genotype analysis of the neuropeptide Y (NPY) Y1 and NPY Y5 receptor genes in gonadotropin-releasing hormone–dependent precocious gonadarche Mandi Barker-Gibb,

Evaluating the role of exogenous luteinizing hormone in poor responders undergoing in vitro fertilization with gonadotropin-releasing hormone antagonists

The gonadotropin-releasing hormone (GnRH)-1 gene, the GnRH receptor gene, and their promoters in patients with idiopathic hypogonadotropic hypogonadism.

Increased pregnancy rates after ultralong postoperative therapy with gonadotropin- releasing hormone analogs in patients with endometriosis Dagmar Rickes,

Chenming Xu, Ph. D. , Bingsen Xu, M. Sc. , Hefeng Huang, M. D

Ovarian hyperstimulation syndrome prevention by gonadotropin-releasing hormone agonist triggering of final oocyte maturation in a gonadotropin-releasing.

In vitro viability and secretory capacity of human luteinized granulosa cells after gonadotropin-releasing hormone agonist trigger of oocyte maturation

Emotional adaptation following successful in vitro fertilization

Prevalence of hypospadias in grandsons of women exposed to diethylstilbestrol during pregnancy: a multigenerational national cohort study Nicolas Kalfa,

Evaluation of intrauterine insemination practices: a 1-year prospective study in seven French assisted reproduction technology centers Oriana Monraisin,

Presentation transcript:

Spontaneous pregnancy in a patient who was homozygous for the Q106R mutation in the gonadotropin-releasing hormone receptor gene Didier Dewailly, M.D., Anne Boucher, M.D., Christine Decanter, M.D., Jean Pierre Lagarde, Ph.D., Raymond Counis, Ph.D., Marie-Laure Kottler, M.D., Ph.D. Fertility and Sterility Volume 77, Issue 6, Pages 1288-1291 (June 2002) DOI: 10.1016/S0015-0282(02)03102-3

FIGURE 1 Automatic DNA sequencing showing the patient’s nucleotide mutation (II2) and segregation analysis of her family. Half-solid symbols indicate unaffected heterozygous persons and the open symbol indicates a nonstudied subject. Dewailly. Spontaneous pregnancy and resistance to GnRH. Fertil Steril 2002. Fertility and Sterility 2002 77, 1288-1291DOI: (10.1016/S0015-0282(02)03102-3)