The General Linear Model

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Presentation transcript:

The General Linear Model Data Design Matrix filter intrinsic correlations and non-sphericity correction contrast images SPM{T}

SPM{T} isoluminant stimuli (even) isochromatic stimuli (odd) V5 speed

contrast 100 SPM{T} PPM 200 300 1 2 3 4 Design matrix z = 3mm z = 3mm

Temporal basis functions Single HRF FIR model Stimulus function Design matrix SPM{F}

neuronal input hidden states hemodynamics BOLD response

Nonlinear saturation

Attention Photic SPC V1 IFG V5 Motion .52 (98%) .37 (90%) .42 (100%) .56 (99%) V1 .69 (100%) IFG .47 (100%) ..82 (100%) V5 Motion .65 (100%)

inhibitory interneurons Extrinsic lateral connections Extrinsic forward connections spiny stellate cells inhibitory interneurons pyramidal cells Intrinsic connections Extrinsic backward connections Neuronal model

inhibitory interneurons spiny stellate cells inhibitory interneurons pyramidal cells Intrinsic Forward Backward Lateral time input .56/.61 .59/.87 .05/.04 .00/.09 .01/3.68 P300 Real and modelled frequent rare