W.J. Anderst, M.S., C. Les, D.V.M., Ph.D., S. Tashman, Ph.D. 

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In vivo serial joint space measurements during dynamic loading in a canine model of osteoarthritis  W.J. Anderst, M.S., C. Les, D.V.M., Ph.D., S. Tashman, Ph.D.  Osteoarthritis and Cartilage  Volume 13, Issue 9, Pages 808-816 (September 2005) DOI: 10.1016/j.joca.2005.04.019 Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

Fig. 1 Reconstructed bones and distance maps. (a) The surface mesh for the femur (top) and tibia (bottom). (b) The articulating surfaces of the femur (top) and tibia (bottom), with the joint “opened up”. Surface triangles were colored according to their minimum distance to the opposing bone surface. Color variations represent 0.5mm changes in distance between subchondral bone surfaces, starting with surfaces ≤0.5mm apart colored red and ending with surfaces ≤4.5mm apart colored dark blue. Osteoarthritis and Cartilage 2005 13, 808-816DOI: (10.1016/j.joca.2005.04.019) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

Fig. 2 Calculating FJS score. (a) Minimum distance maps for five instants of the analyzed motion. Time t=0.00s was the time of pawstrike. (b) The overall minimum distance map, showing the closest values for every surface triangle during the entire motion (pawstrike to 0.20s after pawstrike). (c) FJS scores using the closest 200mm2 area within each compartment (medial and lateral femur; medial and lateral tibia). Color scale is the same as Fig. 1(b), plus white triangles indicate overlap of subchondral joint surfaces. Osteoarthritis and Cartilage 2005 13, 808-816DOI: (10.1016/j.joca.2005.04.019) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

Fig. 3 India ink staining of articulating surfaces (top) and meniscal photos (bottom). (a) A joint with little or no cartilage damage and an intact meniscus. (b) A joint with minor cartilage damage and torn medial meniscus. (c) A joint with severe cartilage damage and destroyed medial meniscus. Scores for each compartment are displayed under the respective photographs. Osteoarthritis and Cartilage 2005 13, 808-816DOI: (10.1016/j.joca.2005.04.019) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

Fig. 4 Change in medial FJS scores (±standard error) relative to pre-CCL transection. Osteoarthritis and Cartilage 2005 13, 808-816DOI: (10.1016/j.joca.2005.04.019) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

Fig. 5 Change in lateral FJS scores (±standard error) relative to pre-CCL transection. Osteoarthritis and Cartilage 2005 13, 808-816DOI: (10.1016/j.joca.2005.04.019) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions