Effect of varying frequency, intensity, and pulse duration of transcutaneous electrical nerve stimulation on primary hyperalgesia in inflamed rats Priya.

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Effect of varying frequency, intensity, and pulse duration of transcutaneous electrical nerve stimulation on primary hyperalgesia in inflamed rats Priya Gopalkrishnan, MS, Kathleen A. Sluka, PhD Archives of Physical Medicine and Rehabilitation Volume 81, Issue 7, Pages 984-990 (July 2000) DOI: 10.1053/apmr.2000.5576 Copyright © 2000 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

Fig. 1 The PWL to heat after TENS treatment for the ipsilateral (open symbols) and the contralateral (closed symbols). Control animals (circles) are represented for comparison on each graph. TENS was applied (arrow) to the inflamed hindpaw 4 hours after injection of carrageenan. *Significantly different from controls or low frequency (p <.01) Archives of Physical Medicine and Rehabilitation 2000 81, 984-990DOI: (10.1053/apmr.2000.5576) Copyright © 2000 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

Fig. 2 Box plots represent the mechanical withdrawal threshold from von Frey filaments before, 4 hours postcarrageenan and post-TENS. The boxes represent the 25th and 75th percentile, with error bars representing the 5th and 95th percentile. The thick bar represents the median. Groups are: C = control; HF = high frequency; LF = low frequency; HI = high intensity (motor); LI = low intensity (sensory); HP = high pulse duration, 250μsec; LP = low pulse duration. *Significantly different from controls, p <.01. Archives of Physical Medicine and Rehabilitation 2000 81, 984-990DOI: (10.1053/apmr.2000.5576) Copyright © 2000 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

Fig. 3 Box plots representing the spontaneous pain-related behaviors after inflammation and after treatment with TENS. The box represents the 25th and 75th percentile. Thick bars represent median values. See fig 2 legend for group definition. *Significantly different from controls, p <.01. Archives of Physical Medicine and Rehabilitation 2000 81, 984-990DOI: (10.1053/apmr.2000.5576) Copyright © 2000 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions