Early-life domestic aeroallergen exposure and IgE sensitization at age 4 years Matias Torrent, MD, MPH, Jordi Sunyer, MD, PhD, Laura Muñoz, PhD, Paul.

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Presentation transcript:

Early-life domestic aeroallergen exposure and IgE sensitization at age 4 years Matias Torrent, MD, MPH, Jordi Sunyer, MD, PhD, Laura Muñoz, PhD, Paul Cullinan, MD, FRCP, Maria Victoria Iturriaga, MSc, Cecilia Figueroa, MD, PhD, Oriol Vall, MD, PhD, Anthony Newman Taylor, MSc, FRCP, Josep Maria Anto, MD, PhD Journal of Allergy and Clinical Immunology Volume 118, Issue 3, Pages 742-748 (September 2006) DOI: 10.1016/j.jaci.2006.04.059 Copyright © 2006 American Academy of Allergy, Asthma and Immunology Terms and Conditions

Fig 1 Probability (logit scale) of sensitization to house dust mite (Der p 1) allergen at age 4 years and house dust mite allergen concentration in early life. Vertical dotted lines indicate tertile cutoff points (0.83 and 6.46 μg/g of dust). Upper left panel, Ashford; upper right panel, Barcelona; lower left panel, Menorca; lower right panel, all centers. Journal of Allergy and Clinical Immunology 2006 118, 742-748DOI: (10.1016/j.jaci.2006.04.059) Copyright © 2006 American Academy of Allergy, Asthma and Immunology Terms and Conditions

Fig 2 Probability (logit scale) of sensitization to cat allergen (Fel d 1) at age 4 years and cat allergen concentration in early life. Vertical dotted lines indicate tertile cutoff points (0.25 and 1.39 μg/g of dust). The Barcelona center is on a different scale of probability of sensitization because of CI limits at high exposures. Upper left panel, Ashford; upper right panel, Barcelona; lower left panel, Menorca; lower right panel, all centers. Journal of Allergy and Clinical Immunology 2006 118, 742-748DOI: (10.1016/j.jaci.2006.04.059) Copyright © 2006 American Academy of Allergy, Asthma and Immunology Terms and Conditions