DHA induces the formation of Pex11pβ-rich regions on elongated peroxisomes. DHA induces the formation of Pex11pβ-rich regions on elongated peroxisomes.

Slides:

Advertisements

Similar presentations

Studies of protein trap expression We compared the apparent intensity of GFP-protein staining in the GSCs with the RNA level of the corresponding gene.

Advertisements

Volume 133, Issue 5, Pages e1 (November 2007)

Michael W. Linhoff, Saurabh K. Garg, Gail Mandel Cell

Dynamics of cell–cell repulsion regulated by PYK2 localized at focal adhesions in migrating cells. Dynamics of cell–cell repulsion regulated by PYK2 localized.

Volume 15, Issue 6, Pages (March 2005)

Fig. 4. Specific versus nonspecific NP accumulation.

Inter-α inhibitor proteins maintain neutrophils in a resting state by regulating shape and reducing ROS production by Soe Soe Htwe, Hidenori Wake, Keyue.

Endogenous MOSPD2 is recruited to interorganelle contact sites by FFAT‐containing proteins Endogenous MOSPD2 is recruited to interorganelle contact sites.

STED microscopy of MINOS

Peroxisomal biogenesis deficiency in skin fibroblasts from a patient with PEX14 mutation. Peroxisomal biogenesis deficiency in skin fibroblasts from a.

Detection and tracking of individual SNAP-tagged proteins on the surface of living cells. Detection and tracking of individual SNAP-tagged proteins on.

The ER is the main source of cholesterol accumulated by STARD3 in endosomes The ER is the main source of cholesterol accumulated by STARD3 in endosomes.

TrkB-T1 is upregulated in cerebellum of Pex14ΔC/ΔC BL/ICR mouse at P3.

Axonal swelling and impairment of dendritic development in Purkinje cells from Pex14ΔC/ΔC BL/ICR mouse upon treatment with BDNF. Axonal swelling and impairment.

Figure 1 VGCC antibody uptake in cerebellar slice culture

Structure and Function of an Actin-Based Filter in the Proximal Axon

BDNF expression in the cerebellum and brain stem region.

The Bacterial Cytoskeleton

Impaired TrkB signaling in the cerebellum of Pex14ΔC/ΔC BL/ICR mice.

Volume 2, Issue 6, Pages (December 2012)

Fig. 3 CSF1 is expressed in human melanoma.

Endolysosomal proteins are exported from the Golgi complex in two distinct populations of transport carriers. Endolysosomal proteins are exported from.

DIA1(R1204X) induces elongated and thick microvilli in HeLa cells

Volume 10, Issue 8, Pages (March 2015)

Nuclear DNA signal is altered in Chd5-deficient NSCs.

Differential secretion profiles of C. elegans TTR models.

Up-regulation of BDNF induces the neurite outgrowth of SH-SY5Y cells.

Occurrence of prominin-1-containing particles in the ventricular fluid of the embryonic mouse brain. Occurrence of prominin-1-containing particles in the.

Fig. 3 Conserved genomic association of PRC1 activity in different leukemic cells. Conserved genomic association of PRC1 activity in different leukemic.

Remodeling and maturation of the mouse retinal vasculature.

Embryonic corneal defects in E18.5 AP-2β NCC KO mutant embryos.

Fig. 1. γ-Tubulin localizes in close proximity to centriole walls in interphase but within an extended PCM meshwork in mitosis.U2OS cells were fixed and.

Fcp1 CTD phosphatase affects a broad range of transcripts in the +N and -N media. Fcp1 CTD phosphatase affects a broad range of transcripts in the +N and.

Robo3 in the GnRH neuronal system.

Fig. 5. The bulk of Cep135 localizes distantly from Sas-6 and STIL

Fig. 2. Centrosomal proteins display distinct localizations and radial distances from centriole walls.U2OS cells were fixed and stained with the indicated.

MET/β-catenin complexes during synapse development.

ArfGAP1 expression alters GBF1 recruitment to Golgi membranes.

Fig. 2. Immunostaining for ClC-5 in isolated hog gastric mucosa

Fig. 4. Perinuclear dynein regulators are not required for primary ciliogenesis.RPE cells were transfected with siRNA and either nocodazole-treated, fixed,

Exo70 is recruited to the plasma membrane at sites of mechanical wounding. Exo70 is recruited to the plasma membrane at sites of mechanical wounding. NRK.

Functional role of DLPI in peroxisome proliferation.

DHA induces peroxisome elongation and division in a Pex11pβ-dependent manner. DHA induces peroxisome elongation and division in a Pex11pβ-dependent manner.

Immunofluorescence analysis of GpGCS1 localization in strains K41 (mating-type plus) and K34 (mating-type minus). Immunofluorescence analysis of GpGCS1.

DHA restores peroxisome morphogenesis in AOx- and D-BP-defective fibroblasts. DHA restores peroxisome morphogenesis in AOx- and D-BP-defective fibroblasts.

Association of peroxisomes with microtubules is required for proper distribution but not division. Association of peroxisomes with microtubules is required.

Lysine residues in the cytoplasmic region of TfR are involved in the MARCH8-induced downregulation of TfR. Lysine residues in the cytoplasmic region of.

E4-ORF1 disrupts proper TJ localization of ZO-1 and ZO-2 in MDCK cells

Model of DHA-mediated peroxisome division.

Proliferation on soft matrices is decoupled from myosin light chain phosphorylation, cell tractions, and focal adhesions. Proliferation on soft matrices.

Fig. 5. Testis defects in STK35 KO mice.

Fig. 1. Rnd2 and Rnd3 induce stress fibres whereas Rnd1 reduces stress fibres in endothelial cells.(A) Rnd mRNAs are expressed in HUVECs. Total RNA was.

Fig. 1. Expression of a Ror-eGFP fusion protein under control of the endogenous Ror promoter in Drosophila embryos. Expression of a Ror-eGFP fusion protein.

PtdIns(4,5)P2 dependence of TbEpsinR and TbCALM membrane targeting.

Dynamic and polarized recruitment of ERC1a near protrusive sites during migration. Dynamic and polarized recruitment of ERC1a near protrusive sites during.

Ubiquitin mediates the interaction between Smo and Vps36.

Subnuclear localization of HA-tagged EBNA1 protein.

Detection and classification of dendritic spines in transfected hippocampal neurons. Detection and classification of dendritic spines in transfected hippocampal.

Domain 3, comprising the basolateral calyx and the stretch of axon leading to the heminode, selectively expressed NaV channels, KCNQ3, and certain scaffolding.

Expression of p130CAS in primary culture neurons

Selective expression of Neurod6 in mDA neurons in the VTA

CDCP1 colocalizes and interacts with MT1-MMP.

Calcium release through TRPML1 controls myosin IIA retrograde flow at the rear of LPS-DCs. Calcium release through TRPML1 controls myosin IIA retrograde.

GSDMD localizes to the plasma membrane and is processed during NET formation. GSDMD localizes to the plasma membrane and is processed during NET formation.

Functional assessment of NF-κB activation in SKBR3 cells.

Lung tumors in KrasLA1 mice are fibrotic.

Activation of Ccl2–Ccr2 pathway is required for mammary carcinogenesis induced by Rb deficiency. Activation of Ccl2–Ccr2 pathway is required for mammary.

Vacuolar Uptake of LDs Under Dark-Induced Starvation.

Paracrine signaling enhances cytokine secretion by isolated cells.

Cellular localization of Panx1 and altered membrane morphology in stable Panx1-transfected C6 glioma cells. Cellular localization of Panx1 and altered.

Presentation transcript:

DHA induces the formation of Pex11pβ-rich regions on elongated peroxisomes. DHA induces the formation of Pex11pβ-rich regions on elongated peroxisomes. (A) AOx-deficient fibroblasts were cultured in the absence (Aa–Ac) or presence (Ad–Ai) of 150 μM DHA for 12 hours and then stained with antibodies to Pex14p (Aa,Ad,Ag) and Pex11pβ (Ab,Ae,Ah); the merged view of the two proteins is shown in Ac, Af and Ai. Insets are higher-magnification images of the boxed regions. Scale bars: 10 μm and 1 μm (insets). Arrowheads indicate regions enriched with Pex11pβ compared with Pex14p. The numbers 1, 2 and 3 correspond to those in panel B. (B) Mutually distinct peaks of Pex11pβ and Pex14p were apparent upon in-line scanning of the transecting line shown in Ag–Ai. The intensity of Pex11pβ signals was significantly increased at regions (arrowheads) that did not contain Pex14p. Akinori Itoyama et al. J Cell Sci 2012;125:589-602 © 2012.