17. Immunologic endocrine disorders

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Presentation transcript:

17. Immunologic endocrine disorders Devasenan Devendra, MD, George S. Eisenbarth, MD, PhD Journal of Allergy and Clinical Immunology Volume 111, Issue 2, Pages S624-S636 (February 2003) DOI: 10.1067/mai.2003.81 Copyright © 2003 Mosby, Inc. Terms and Conditions

Fig. 1 HBDI (Human Biologic Disease Interchange) Series: Transmission from parents with second haplotype not DQ2 or DQ8. Journal of Allergy and Clinical Immunology 2003 111, S624-S636DOI: (10.1067/mai.2003.81) Copyright © 2003 Mosby, Inc. Terms and Conditions

Fig. 2 Prevalence of transglutaminase autoantibodies by HLA-DR among patients with type 1 diabetes mellitus, relatives of patients with diabetes mellitus, and general population. (Teaching slides, Type 1 Diabetes: Cellular, molecular and clinical immunology. Eisenbarth GS, editor. www.barbaradaviscenter.org ). Journal of Allergy and Clinical Immunology 2003 111, S624-S636DOI: (10.1067/mai.2003.81) Copyright © 2003 Mosby, Inc. Terms and Conditions

Fig. 3 Progression to diabetes versus number of autoantibodies (GAD, ICA512 [IA-2], Insulin). Copyright © 1996, American Diabetes Association. From Diabetes, Vol 45. 1996. p. 926-33. Reprinted with permission from The American Diabetes Association. Journal of Allergy and Clinical Immunology 2003 111, S624-S636DOI: (10.1067/mai.2003.81) Copyright © 2003 Mosby, Inc. Terms and Conditions