Elevated serum concentrations of erythropoietin after xenon anaesthesia in cardiac surgery: secondary analysis of a randomized controlled trial C. Stoppe,

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Elevated serum concentrations of erythropoietin after xenon anaesthesia in cardiac surgery: secondary analysis of a randomized controlled trial C. Stoppe, M. Coburn, A. Fahlenkamp, J. Ney, S. Kraemer, R. Rossaint, A. Goetzenich British Journal of Anaesthesia Volume 114, Issue 4, Pages 701-703 (April 2015) DOI: 10.1093/bja/aev060 Copyright © 2015 The Author(s) Terms and Conditions

Fig 1 Perioperative serum concentrations of erythropoietin (a), testosterone (b), and haemoglobin (c). (a) There was a significant increase (*) of serum erythropoietin concentrations after xenon anaesthesia from the preoperative value to the first postoperative day (24 h later), whereas no significant change was observed in the sevoflurane group. Serum concentrations of erythropoietin showed a trend towards difference between both groups on the first postoperative day (P=0.051). (b) No significant change or difference between groups was observed with respect to the measured testosterone concentrations. (c) Circulating concentrations of haemoglobin trended to be higher in the xenon group throughout the postoperative course. All data were analysed by two-way anova or Student's unpaired t-test where appropriate (Prism-6, GraphPad Software Inc., La Jolla, CA, USA; SPSS-21, IBM Corporation, Armonk, NY, USA) to compare differences at distinct time points. British Journal of Anaesthesia 2015 114, 701-703DOI: (10.1093/bja/aev060) Copyright © 2015 The Author(s) Terms and Conditions