Frequency and Carrier Risk Associated with Common BRCA1 and BRCA2 Mutations in Ashkenazi Jewish Breast Cancer Patients Flora H. Fodor, Ainsley Weston,

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Frequency and Carrier Risk Associated with Common BRCA1 and BRCA2 Mutations in Ashkenazi Jewish Breast Cancer Patients Flora H. Fodor, Ainsley Weston, Ira J. Bleiweiss, Leslie D. McCurdy, Mary M. Walsh, Paul I. Tartter, Steven T. Brower, Christine M. Eng The American Journal of Human Genetics Volume 63, Issue 1, Pages 45-51 (July 1998) DOI: 10.1086/301903 Copyright © 1998 The American Society of Human Genetics Terms and Conditions

Figure 1 A representative dot-blot hybridization of the PCR products hybridized by allele-specific oligonucleotides complementary to the normal allele (left panel) and to the 6174delT mutant allele (right panel). A positive control is shown in the upper-right corner, preceded by a DNA blank; two patients were heterozygous for the mutation. Amplification failures were noted. The American Journal of Human Genetics 1998 63, 45-51DOI: (10.1086/301903) Copyright © 1998 The American Society of Human Genetics Terms and Conditions