Merging the Art and Science of Managing nOH in Clinical Practice
Definitions of OH and nOH
Pathophysiology of OH and nOH
Case Study
Patients in 5 Categories at Higher Risk for OH or nOH
Screening Questions for Suspected OH or nOH
How to Diagnose OH Features Suggestive of nOH
Diagnosis of nOH in Individuals Who Screen Positive for OH If the Diagnosis is OH and not nOH
Common Medications That May Cause OH or Exacerbate the Symptoms of nOH
Consensus Panel Recommendations Supine Hypertension and nOH
Treatment Algorithm for nOH
Treating nOH – Step 1 Review and Adjust Current Medications
Treating nOH – Step 2 Nonpharmacologic Measures
Treating nOH – Step 2 Nonpharmacologic Measures (cont)
Treating nOH – Step 2 Nonpharmacologic Measures (cont)
Treating nOH – Step 3 Initial Pharmacologic Treatment
Pharmacologic Options Fludrocortisone
Pharmacologic Options Midodrine
Pharmacologic Options Droxidopa
Pharmacologic Options Pyridostigmine
Mechanisms of Action of Investigational Therapies
Assessing nOH Treatment Success
Concluding Remarks
Abbreviations