Model of ILD sensitivity in the LSO. A, Circuit diagram.

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Model of ILD sensitivity in the LSO. A, Circuit diagram. Model of ILD sensitivity in the LSO. A, Circuit diagram. Each large circle is modeled by a nonlinear input–output function (Reed and Blum, 1999). Black disks indicate excitatory synapses (weight 1). The white disk indicates the inhibitory synapse from MNTB to LSO. AN indicates auditory nerve. B, Three examples of ILD response functions from the model (lines) and data points (symbols) to which the model is fitted. C, Mean inhibitory weights calculated from fits to response functions for the three groups of animals. Error bars indicate SEM. *p < 0.05 for an unpaired t test. Ida Siveke et al. J. Neurosci. 2012;32:462-473 ©2012 by Society for Neuroscience