Key apical membrane ion transporters and channels in various segments of the gastrointestinal tract. Key apical membrane ion transporters and channels.

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Presentation transcript:

Key apical membrane ion transporters and channels in various segments of the gastrointestinal tract. Key apical membrane ion transporters and channels in various segments of the gastrointestinal tract. The driving force for most absorption and secretion across the apical membrane is the basolateral Na+/K+-ATPase shown. All other basolateral ion transporters and channels are deliberately omitted. CFTR, cystic fibrosis transmembrane conductance regulator; DRA, downregulated in adenoma gene product; SCFA, short-chain fatty acids. F. John Gennari, and Wolfgang J. Weise CJASN 2008;3:1861-1868 ©2008 by American Society of Nephrology