Propofol: Milk of Amnesia

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Propofol: Milk of Amnesia Christopher T. Walsh Cell Volume 175, Issue 1, Pages 10-13 (September 2018) DOI: 10.1016/j.cell.2018.08.031 Copyright © 2018 Elsevier Inc. Terms and Conditions

Figure 1 Several Anesthetics Target the GABA Receptor (A) Structures of morphine and several synthetic anesthetic agents. The in vivo metabolism of propofol to water-soluble glucuronides and sulfates is shown. (B) Schematic of the pentameric GABAA-gated ion channel and sites for binding of small molecules including the anesthetics propofol, etomidate, and desflurane. Adapted from Lovinger (2008). Cell 2018 175, 10-13DOI: (10.1016/j.cell.2018.08.031) Copyright © 2018 Elsevier Inc. Terms and Conditions