Effects of pterosin A on serum levels of lipid, blood urea nitrogen (BUN), creatinine, aspartate aminotransferase (AST), and alanine aminotransferase (ALT)

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Effects of pterosin A on serum levels of lipid, blood urea nitrogen (BUN), creatinine, aspartate aminotransferase (AST), and alanine aminotransferase (ALT) in HFD-fed or STZ-induced diabetic mouse (DM) models. Effects of pterosin A on serum levels of lipid, blood urea nitrogen (BUN), creatinine, aspartate aminotransferase (AST), and alanine aminotransferase (ALT) in HFD-fed or STZ-induced diabetic mouse (DM) models. The HFD-feeding or STZ-induced diabetic mice were orally treated with pterosin A (100 mg/kg) for 4 weeks. Serum lipids (total cholesterol, triglyceride, LDL-cholesterol, HDL-cholesterol) (A and B), BUN and creatinine (C), and AST and ALT (D) levels were measured in fasting mice. Data are presented as mean ± SEM (n = 8). *P < 0.05 vs. control. #P < 0.05 vs. STZ or HFD diabetic mice without pterosin A. Feng-Lin Hsu et al. Diabetes 2013;62:628-638 ©2013 by American Diabetes Association