A: Chemical structure of pterosin A A: Chemical structure of pterosin A. Effects of pterosin A on hyperglycemia, glucose intolerance, and body weight in a STZ-induced diabetic mouse (DM) model. A: Chemical structure of pterosin A. Effects of pterosin A on hyperglycemia, glucose intolerance, and body weight in a STZ-induced diabetic mouse (DM) model. The STZ-induced diabetic mice were orally treated with pterosin A (10–100 mg/kg) for 4 weeks, and the oral glucose tolerance test was performed (B) and the body weights were measured (C). D: Mice were pretreated with pterosin A for 3 days, STZ was injected, and the oral glucose tolerance test was performed after 1 week. Data are presented as mean ± SEM (n = 8). *P < 0.05 vs. diabetic mice without pterosin A; #P < 0.05 vs. diabetic mice alone. Feng-Lin Hsu et al. Diabetes 2013;62:628-638 ©2013 by American Diabetes Association