Frederika A. van Nimwegen, MSc, John Penders, PhD, Ellen E

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Presentation transcript:

Mode and place of delivery, gastrointestinal microbiota, and their influence on asthma and atopy Frederika A. van Nimwegen, MSc, John Penders, PhD, Ellen E. Stobberingh, PhD, Dirkje S. Postma, MD, PhD, Gerard H. Koppelman, MD, PhD, Marjan Kerkhof, MD, PhD, Naomi E. Reijmerink, MD, PhD, Edward Dompeling, MD, PhD, Piet A. van den Brandt, PhD, Isabel Ferreira, PhD, Monique Mommers, PhD, Carel Thijs, MD, PhD Journal of Allergy and Clinical Immunology Volume 128, Issue 5, Pages 948-955.e3 (November 2011) DOI: 10.1016/j.jaci.2011.07.027 Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Mediation model. The relation between the antecedent variable mode of delivery on the dependent variable allergic manifestations is mediated through C difficile. a Represents the strength of the relation between mode of delivery and C difficile, b represents the strength of the association between C difficile and the allergic outcomes, and c′ represents the strength of the relation between mode of delivery and the allergic outcomes. Journal of Allergy and Clinical Immunology 2011 128, 948-955.e3DOI: (10.1016/j.jaci.2011.07.027) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 Population flow chart. Journal of Allergy and Clinical Immunology 2011 128, 948-955.e3DOI: (10.1016/j.jaci.2011.07.027) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E2 Prevalence of wheeze. Journal of Allergy and Clinical Immunology 2011 128, 948-955.e3DOI: (10.1016/j.jaci.2011.07.027) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E3 Prevalence of eczema. Journal of Allergy and Clinical Immunology 2011 128, 948-955.e3DOI: (10.1016/j.jaci.2011.07.027) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions