Schematic representation of phase cancellation and temporal dispersion in demyelination.  Schematic representation of phase cancellation and temporal.

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 Schematic representation of phase cancellation and temporal dispersion in demyelination.  Schematic representation of phase cancellation and temporal dispersion in demyelination. In the normal nerve, the responses are synchronised in time and therefore summate (amplitude is higher that that of the individual components). Temporal dispersion results in an increased duration and reduced amplitude of CMAP. A Mallik, and A I Weir J Neurol Neurosurg Psychiatry 2005;76:ii23-ii31 ©2005 by BMJ Publishing Group Ltd