Schematic representation of the immunization regimens used in this study. Schematic representation of the immunization regimens used in this study. BALB/c.

Slides:

Advertisements

Similar presentations

$100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300 $400 $500 $100 $200 $300.

Advertisements

Copenhagen, 5 March 2015 Identification of the most immunogenic/protective VLP-HA construct in mice Department of Immunology Development of a universal.

Oncolytic Viruses: Therapeutics With an Identity Crisis

Vaccines for the elderly

Phylogenetic characterization of the Bunyavirales-like viruses identified in this study. Phylogenetic characterization of the Bunyavirales-like viruses.

Copyrights apply.

Serum IgG (A–D) and IgA (E–H) titer from BALB/c mice (n = 5/group) at day 0 or following COBRA P1 virus i.n., i.p., or i.m. prime at day 21 or following.

Schematic representation of possible effects of different factors on systemic resilience. Schematic representation of possible effects of different factors.

A Prize for Cancer Prevention

Volume 25, Issue 6, Pages (June 2017)

Type 17 immunity is increased in STAT1−/− mice.

RNA Interference in Mammals: The Virus Strikes Back

RNA Interference in Mammals: The Virus Strikes Back

Preferential infection of CD1c+ DCs by HIV-1, HIV-2, and influenza virus. Preferential infection of CD1c+ DCs by HIV-1, HIV-2, and influenza virus. (A)

N. Clementi, F. Cappelletti, E. Criscuolo, M. Castelli, N. Mancini, R

Targeted DNA vaccination induced protection against nasal challenge with influenza virus 14 d after DNA vaccination. Targeted DNA vaccination induced protection.

Breadth of binding and HAI activity of serum Ab from i. n. + i. p

Alternative vector control methods to manage the Zika virus outbreak: more haste, less speed – Authors' reply Laith Yakob, Thomas Walker The Lancet.

(A) Weight loss curves following intranasal infection of different mouse groups with COBRA, seasonal, or pandemic influenza viruses. (A) Weight loss curves.

Long-lasting protection against nasal challenge with influenza virus 252 d after a single DNA vaccination. Long-lasting protection against nasal challenge.

LV DNA, genome, and capsid are not required for DC activation and CD8+ T cell priming in vivo. LV DNA, genome, and capsid are not required for DC activation.

IL-10 treatment increases restorative macrophage (MΦ) bias and function in chronically infected skeletal muscle. IL-10 treatment increases restorative.

A. Oliver, A. Mena Clinical Microbiology and Infection

Serum IgG subclass representation from BALB/c mice (n = 5/group) following COBRA P1 virus i.n., i.p., or i.m. prime followed by i.p. or i.m. boost. Serum.

Virus-specific serum antibody response of BALB/c mice to DNA prime followed by VRP boost. Virus-specific serum antibody response of BALB/c mice to DNA.

Volume 26, Issue 2, Pages (February 2018)

VLPs activate DCs and antigen-specific CD8+ T cells via the STING and cGAS pathway. VLPs activate DCs and antigen-specific CD8+ T cells via the STING and.

Virus-specific serum antibody response of BALB/c mice to DNA prime followed by VRP boost. Virus-specific serum antibody response of BALB/c mice to DNA.

GM-CSF–producing γδT cells are involved in the development of EAM

Fluorescence-based in vivo imaging of MSP.

STAT3 regulates IgE class switching in a Th2-type response.

Nonhematopoietic cells help regulate the pathogenic adaptive immune response during the second peak of joint swelling. Nonhematopoietic cells help regulate.

IL-27–eGFP is highly expressed by cDC1 cells and Ly6Chi monocytes after vaccine adjuvant administration. IL-27–eGFP is highly expressed by cDC1 cells and.

Serum neutralizing antibody response of BALB/c mice to DNA prime followed by VRP boost. Serum neutralizing antibody response of BALB/c mice to DNA prime.

Therapeutic administration of Areg increases restorative macrophages (MΦ) and reduces Tbet expression in Tregs during infection. Therapeutic administration.

IL-33 treatment improves restorative macrophages (MΦ) but not function

Extracellular mitochondria cause neutrophil recruitment.

Rachel Guiton, Marc Dalod Cell Host & Microbe

Schematic representation of hepatitis E virus (HEV) genotype 3 in developed countries. Schematic representation of hepatitis E virus (HEV) genotype 3 in.

Vaccines for the elderly

N. Clementi, F. Cappelletti, E. Criscuolo, M. Castelli, N. Mancini, R

Resistance of CD141+ DCs to influenza virus in vivo in humanized mice.

Schematic representation of our random walk model with environmental state-dependent dynamics. Schematic representation of our random walk model with environmental.

Ag 85A–specific immune responses.

Tfr cell–derived IL-10 is important for B cell differentiation and the GC response. Tfr cell–derived IL-10 is important for B cell differentiation and.

IL-27 contributes to IR expression by lung T cells during toxoplasmosis. IL-27 contributes to IR expression by lung T cells during toxoplasmosis. (A) Il27p28-GFP.

AN12855 is efficacious in acute and chronic murine models of TB infection. AN12855 is efficacious in acute and chronic murine models of TB infection. (A,

Experimental design for serological analyses.

Comparison of male and female CD8+ T cells primed with different amounts of cognate Ag. (A) Schematic of experimental design: 1 × 104 gBT-I CD8+ T cells.

Chimeric HA-based universal influenza virus vaccine concept.

IFN-γ–producing cells in the spleen and lungs postimmunization.

NKTfh cell–driven class switch against polysaccharide Ag is IL-21-influenced. NKTfh cell–driven class switch against polysaccharide Ag is IL-21-influenced.

Prime and boosts with PBK001 vaccine provided 100% protection with low bacterial burden in organs. Prime and boosts with PBK001 vaccine provided 100% protection.

Ado loss drives TNF-dependent immune evasion.

Hepatitis E in the United States: A Case of “Hog Fever”?

Schematic representation of the progress in the development of vaccines against the most recent pandemic and seasonal H1N1 influenza virus strains. Schematic.

Survival and tumor burden of mice bearing peritoneally disseminated gastric cancer. Survival and tumor burden of mice bearing peritoneally disseminated.

Anti-Flk-1 treatment inhibits growth of s. c. 4T1 and B16 tumors. s. c

Immunization regimens that include a GLA-SE-formulated protein vaccine generate memory CD4 T cells. Immunization regimens that include a GLA-SE-formulated.

Fig. 6 Multivalent DNA vaccine and protein antigen delivery by T4-AAV nanoparticles. Multivalent DNA vaccine and protein antigen delivery by T4-AAV nanoparticles.

Light microscopic evaluation of bladders and kidneys in E

Schematic representation of the interrelationship between monocyte differentiation, NF-κB accumulation and translocation, and TNF-α secretion. Schematic.

Mean weight change from original weight of (a) BALB/c (b) DBA/2 mice after one (♦) or two (▴) injections of 10 mg/kg and one (▪) or two (×) injections.

In vivo prophylactic and therapeutic efficacy of C12G6 in mice

Pros and cons for neoadjuvant immunotherapy.

Increased accumulation of pmel-1 T cells to tumor sites and enhanced antitumor immune response in mice receiving ACT combined with anti-PD-1 antibody treatment.

Mutation of the Smad3 linker phosphorylation sites in 4T1 cells reduces putative stem cell population and tumor initiating frequency of cells from the.

Fig. 5 Topical vaginal application of DECON on alternate days is as effective as daily systemic ACV dosing. Topical vaginal application of DECON on alternate.

In vivo shRNA screening strategy.

Presentation transcript:

Schematic representation of the immunization regimens used in this study. Schematic representation of the immunization regimens used in this study. BALB/c mice (n = 5/group) were immunized through an i.n. infection with COBRA or H1N1 viruses described in this study and i.p. or i.m. boosted with the homologous virus. Alternatively, mice (n = 5/group) were primed through an i.p. or i.m. immunization containing COBRA P1 virus and again i.p. or i.m. boosted with the homologous virus. Giuseppe A. Sautto et al. ImmunoHorizons 2018;2:226-237 Copyright © 2018 The Authors