Enthesitis in Psoriatic Arthritis: Disease, Diagnosis and Decisions

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Presentation transcript:

Enthesitis in Psoriatic Arthritis: Disease, Diagnosis and Decisions

This program will include a discussion of data that were presented in abstract form. These data should be considered preliminary until published in a peer-reviewed journal.

Program Overview

Introduction

Overview of PsA Heterogeneity and Disease Domains

Typical Presentations of PsA

Challenges/Barriers in Accurate and Timely Diagnosis of PsA Challenges/Barriers in Accurate and Timely Diagnosis of PsA? --Expert Perspective

PsA Eludes Early Diagnosis

Patients have Delays and Misdiagnoses Before they Receive a PsA Diagnosis

Key Factors for a Dermatologist to Overcome Barriers in PsA Diagnosis

When Does a Dermatologist Refer to a Rheumatologist?

Combined Clinics

Evaluating patients with psoriasis for signs and symptoms of PsA

Screening Tools: Questionnaires

Screening Tools: Questionnaires (II)

What Should a Rheumatologist Consider to Overcome Barriers in PsA Diagnosis?

Other Aspects of Optimal Management Between Rheumatologists and Dermatologists

Impact of a Delay in PsA Diagnosis, Why is Early Diagnosis Important?

Delay in Diagnosis > 6 Months Leads to Poorer Outcomes in PsA

What do we know about Enthesitis in PsA Disease?

Value of Ultrasound for Early PsA Diagnosis

Enthesitis vs Synovitis

Which Techniques are used to Identify/Assess Enthesitis?

What is the Immunopathogenesis of Enthesitis?

What Should a Dermatologist Know about Enthesitis? –Expert Perspective

What Treatments are Available for PsA?

Etanercept and Methotrexate in Patients with Psoriatic Arthritis: SEAM - PsA

Enthesitis Outcomes in RCT in PsA: TNFi

Enthesitis Outcomes with Ixekizumab (IL-17i)

Enthesitis Outcomes with Secukinumab (IL-17i)

FUTURE 5: Secukinumab Improved Resolution of Enthesitis in PsA Patients

Enthesitis Outcomes in RCT in PsA: IL-23i

Enthesitis Outcomes in RCT in PsA: PDE4i, T-cell I and JAKi

Recent and Upcoming Head-to-Head Trials Evaluating Enthesitis in PsA

Safety Considerations

Safety Considerations –Expert Perspective (II)

Concluding Remarks

Abbreviations

Abbreviations (cont)

Abbreviations (cont)