Identification of Genetic Markers Associated with Gilles de la Tourette Syndrome in an Afrikaner Population Ingrid Simonic, George S. Gericke, Jurg Ott,

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Identification of Genetic Markers Associated with Gilles de la Tourette Syndrome in an Afrikaner Population Ingrid Simonic, George S. Gericke, Jurg Ott, James L. Weber The American Journal of Human Genetics Volume 63, Issue 3, Pages 839-846 (September 1998) DOI: 10.1086/302002 Copyright © 1998 The American Society of Human Genetics Terms and Conditions

Figure 1 Electrophoretic profiles for markers that demonstrated consistent allele frequency distribution differences between affected and control subjects in the first group. Segments of autoradiographs from polyacrylamide gels are displayed for six STRPs at the indicated loci. The DNA templates used to generate the amplified DNA fragments were in the same order for each marker: standard DNA from CEPH family parents 133101 (1) and 133102 (2), DNA pool from set 1 of unaffected control subjects (C1), DNA pool from set 1 of affected subjects (A1), independent amplification of pools C1 and A1, DNA pool from set 2 of unaffected control subjects (C2), and DNA pool from set 2 of affected subjects (A2). Arrows mark alleles enriched in the affected subjects. Sizes (in nucleotides) for the enriched alleles are listed on the left. The American Journal of Human Genetics 1998 63, 839-846DOI: (10.1086/302002) Copyright © 1998 The American Society of Human Genetics Terms and Conditions