Volume 58, Issue 4, Pages (October 2000)

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Volume 58, Issue 4, Pages 1695-1702 (October 2000) Changes in conjugated linoleic acid and its metabolites in patients with chronic renal failure Leonardo Lucchi, Sebastiano Banni, Maria P. Melis, Elisabetta Angioni, Gianfranca Carta, Viviana Casu, Renato Rapanà, Angela Ciuffreda, Francesco P. Corongiu, Alberto Albertazzi Kidney International Volume 58, Issue 4, Pages 1695-1702 (October 2000) DOI: 10.1046/j.1523-1755.2000.00330.x Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 1 Concentrations of (A) conjugated linoleic acid (CLA), (B) conjugated linolenic acid (CD18:3), (C) conjugated eicosatrienoic acid (CD20:3), and (D) conjugated dienes (CD) fatty acid hydroperoxides in lipids extracted from plasma, adipose tissue, and red blood cell membranes of the various groups studied. Symbols are: (□) controls; (□) CRF patients with CCr> 10 mL/min; (□) CRF patients with CCr <10 mL/min; (▪) hemodialyzed patients. *P < 0.05 between patients and controls. ##Adipose tissue data from patients with CCr> 10 mL/min were omitted because of the small sample number rendering statistical analysis not reliable. Kidney International 2000 58, 1695-1702DOI: (10.1046/j.1523-1755.2000.00330.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 2 Relationship between plasma CLA and predicted CCr in the CRF patients group. The continuous line represents the linear regression (y = -14.23x + 1514.5, R2 = 0.305). The dotted line represents the logarithmic regression [y = -317.9Ln(x) + 2052.5, R2 = 0.442], and the dashed line represents the exponential regression (y = 2292.8x-0.2551, R2 = 0.490). Kidney International 2000 58, 1695-1702DOI: (10.1046/j.1523-1755.2000.00330.x) Copyright © 2000 International Society of Nephrology Terms and Conditions