T cells and T-cell receptors in acute renal failure

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T cells and T-cell receptors in acute renal failure Didier Portilla, Mark D. Okusa Kidney International Volume 69, Issue 2, Pages 208-210 (January 2006) DOI: 10.1038/sj.ki.5000128 Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 1 Two-signal model of lymphocyte activation. Signal 1 corresponds to the binding of the peptide-MHC complex of the antigen-presenting cell to the T-cell receptor. Signal 2 corresponds to the binding of the B7 molecule in the antigen-presenting cell, its CD28 receptor in the T cell. Kidney International 2006 69, 208-210DOI: (10.1038/sj.ki.5000128) Copyright © 2006 International Society of Nephrology Terms and Conditions