Christopher M. Haggerty, PhD, Kevin K

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Relationship of Single Ventricle Filling and Preload to Total Cavopulmonary Connection Hemodynamics Christopher M. Haggerty, PhD, Kevin K. Whitehead, MD, PhD, James Bethel, PhD, Mark A. Fogel, MD, Ajit P. Yoganathan, PhD The Annals of Thoracic Surgery Volume 99, Issue 3, Pages 911-917 (March 2015) DOI: 10.1016/j.athoracsur.2014.10.043 Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Imaging inputs required for total cavopulmonary connection (TCPC) computational fluid dynamics simulations: transverse stack of magnetic resonance images (top left) is the input for segmentation (bottom left) and anatomic reconstruction. Through-plane phase contrast magnetic resonance images (top right; magnitude and inset phase image) to obtain patient-specific flow boundary conditions at the locations indicated on the anatomic reconstruction (bottom right). (IVC = inferior vena cava; LPA = left pulmonary artery; RPA = right pulmonary artery; SSFP = steady-state free precession; SVC = superior vena cava.) The Annals of Thoracic Surgery 2015 99, 911-917DOI: (10.1016/j.athoracsur.2014.10.043) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Representative output for computational fluid dynamics simulations showing time-averaged velocity streamlines and indexed power loss (iPL) for (A) lowest power loss patients and (B) highest power loss patients from among the patients analyzed. In the larger figures, the streamlines are color coded by local velocity magnitude, whereas the streamlines in the smaller, inset images are color coded by vessel of origin: red indicates superior vena cava; blue, inferior vena cava; and green, azygos vein. The Annals of Thoracic Surgery 2015 99, 911-917DOI: (10.1016/j.athoracsur.2014.10.043) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Statistically significant logarithmic correlations observed between indexed power loss and end-diastolic volume (EDV). The Annals of Thoracic Surgery 2015 99, 911-917DOI: (10.1016/j.athoracsur.2014.10.043) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions