Comparison of sedation and general anaesthesia for transcatheter aortic valve implantation on cerebral oxygen saturation and neurocognitive outcome†

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Presentation transcript:

Comparison of sedation and general anaesthesia for transcatheter aortic valve implantation on cerebral oxygen saturation and neurocognitive outcome† N.P. Mayr, A. Hapfelmeier, K. Martin, A. Kurz, P. van der Starre, B. Babik, D. Mazzitelli, R. Lange, G. Wiesner, P. Tassani-Prell British Journal of Anaesthesia Volume 116, Issue 1, Pages 90-99 (January 2016) DOI: 10.1093/bja/aev294 Copyright © 2016 The Author(s) Terms and Conditions

Fig 1 CONSORT Flow Diagram. British Journal of Anaesthesia 2016 116, 90-99DOI: (10.1093/bja/aev294) Copyright © 2016 The Author(s) Terms and Conditions

Fig 2 Perioperative evolution rSO2. (a and b) Green lines show the individual perioperative rSO2 values. The blue line shows the Median and the 25–75th percentile. (c) Cummulative Area under the curve (AUC) for individual patients in both groups below the desaturation (DESAT) threshold. The pink line indicates 3000 s% (d) Perioperative mean arterial pressure. Boxplots show Median, 25–75th percentile, Minimum, Maximum and outliers within 5–95th percentile. TAVI-GA – general anaesthesia, TAVI-S sedation, RVP – Rapid Ventricular Pacing for balloon valvuloplasty. British Journal of Anaesthesia 2016 116, 90-99DOI: (10.1093/bja/aev294) Copyright © 2016 The Author(s) Terms and Conditions

Fig 3 Pre- to postoperative difference in neurocognitive testing. P-values between TAVI-patients in general anaesthesia (TAVI-GA, blue) and sedation (TAVI-S, green). Neurocognitive tests: DemTect, RWT – Regensburger Wortflüssigkeitstest, ZVT – Zahlenverbindungstest part 1 and 2. British Journal of Anaesthesia 2016 116, 90-99DOI: (10.1093/bja/aev294) Copyright © 2016 The Author(s) Terms and Conditions

Fig 4 Blood gas analysis of arterial blood samples. TAVI-GA – general anaesthesia (blue), TAVI-S – Sedation (green). Boxplots show Median, 25–75th percentile, Minimum, Maximum and outliers within 5–95th percentile. British Journal of Anaesthesia 2016 116, 90-99DOI: (10.1093/bja/aev294) Copyright © 2016 The Author(s) Terms and Conditions