Next-Generation Sequencing and ctDNA

This program will include a discussion of data that were presented in abstract form. These data should be considered preliminary until published in a peer-reviewed journal.

Molecular Testing Drives Lung Cancer Therapy

Workflow in Cancer Pathology Laboratory

Key Considerations in Cancer Pathology

Multidisciplinary Collaboration Is Critical More Information Leads to Better Results

Considerations for an Accurate Diagnosis

Right Treatment Requires Correct Diagnosis

Limitations of Biopsy

ctDNA Testing Multiple Assays Now Available

Validation of Rapid Plasma Genotyping in Advanced Lung Cancer

Role of ctDNA Testing Is Evolving

Which Lung Cancer Patients Are Candidates for ctDNA Testing?

Clinical Context Matters

Clinical Context Matters (cont)

Potential Future Directions in Plasma Genotyping

In Whom to Test ctDNA?

Send-Out vs In-House?

Selected ctDNA Assays

What Should Pathologists Know About ctDNA and NGS?

Plasma Genotyping Tradeoffs

Implications for Medical Oncologists

Key Takeaways

Abbreviations