Western blot analysis of α-Syn-BAC-Tg/GBA-hetero-KO mice at multiple time points. Western blot analysis of α-Syn-BAC-Tg/GBA-hetero-KO mice at multiple.

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Western blot analysis of α-Syn-BAC-Tg/GBA-hetero-KO mice at multiple time points. Western blot analysis of α-Syn-BAC-Tg/GBA-hetero-KO mice at multiple time points. Left panels show Western blots of whole cortex (3 males at each time point) with antibodies against pSer46-MARCKS, pSer129-α-Syn, and ubiquitin. Right graphs show quantitative analyses of three independent blots for pSer46-MARCKS, pSer129-α-Syn, and ubiquitin; band intensities were normalized against β-actin. Statistical analyses were performed with two-way ANOVA followed by Student’s t test; *, p < 0.05; **, p < 0.01. (See also Fig. 6-1.)‏ Kyota Fujita et al. eNeuro 2018;5:ENEURO.0217-18.2018 ©2018 by Society for Neuroscience