Increased phosphorylation of Akt, Girdin S1416, and NR2B of NMDA receptor in the hippocampus of mouse after fear conditioning. Increased phosphorylation.

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Presentation transcript:

Increased phosphorylation of Akt, Girdin S1416, and NR2B of NMDA receptor in the hippocampus of mouse after fear conditioning. Increased phosphorylation of Akt, Girdin S1416, and NR2B of NMDA receptor in the hippocampus of mouse after fear conditioning. A–C, Western blot analyses showing the time-course changes in the phosphorylated levels of Akt S473 (A), Girdin S1416 (B), and NR2B Y1472 (C) in the DG. The DG of 8- to 9-week-old mice were removed 5 min, 15 min, or 30 min after fear conditioning. Control mice were placed in a conditioning chamber without shock and tone. Data are expressed as mean ± SEM (n = 5 mice per time point). One-way ANOVA; F(3,16) = 4.795, p < 0.05 for A; F(3,16) = 4.909, p < 0.05 for B; F(3,16) = 4.120, p < 0.05 for C. *p < 0.05 compared with control mice (Tukey–Kramer post hoc test). Tsuyoshi Nakai et al. J. Neurosci. 2014;34:14995-15008 ©2014 by Society for Neuroscience