Metabolic parameters of Id1−/− and wild-type mice fed a standard chow diet (hatched bars and striped bars, respectively) or a high-fat diet (black bars and white bars, respectively) for 6 weeks. Metabolic parameters of Id1−/− and wild-type mice fed a standard chow diet (hatched bars and striped bars, respectively) or a high-fat diet (black bars and white bars, respectively) for 6 weeks. A: Body weight for wild-type (n = 22) and Id1−/− (n = 22) mice fed a chow diet and wild-type (n = 16) and Id1−/− (n = 11) mice fed a high-fat diet. *P < 0.05 for effect of diet in wild-type and Id1−/− mice. B: Epididymal fat pad weight. Results are expressed as a percentage of body weight for wild-type (n = 5) and Id1−/− (n = 6) mice fed a chow diet and wild-type (n = 7) and Id1−/− (n = 7) mice fed a high-fat diet. **P < 0.01 for effect of diet in wild-type and Id1−/− mice. C: Liver weight for wild-type (n = 10) and Id1−/− (n = 6) mice fed a chow diet and wild-type (n = 8) and Id1−/− (n = 6) mice fed a high-fat diet. D: Energy intake of wild-type (n = 9) and Id1−/− (n = 6) mice fed a chow diet and wild-type (n = 12) and Id1−/− (n = 8) mice fed a high-fat diet. ANOVA: P < 0.05 for effect of diet. Mia C. Åkerfeldt, and D. Ross Laybutt Diabetes 2011;60:2506-2514 ©2011 by American Diabetes Association