Gadolinium deposition in nephrogenic fibrosing dermopathy

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Presentation transcript:

Gadolinium deposition in nephrogenic fibrosing dermopathy Alan S. Boyd, MD, John A. Zic, MD, Jerrold L. Abraham, MD Journal of the American Academy of Dermatology Volume 56, Issue 1, Pages 27-30 (January 2007) DOI: 10.1016/j.jaad.2006.10.048 Copyright © 2007 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Scanning electron microscopy, backscattered electron images of cut surface of paraffin block of skin biopsy, low magnification (A), and detail (B), showing dermal vessel wall deposits of calcium, phosphorus, sodium, and gadolinium. Energy dispersive x-ray spectra show major composition of bright areas is sodium-calcium-phosphate (C), with gadolinium detected at much lower concentrations (D). Journal of the American Academy of Dermatology 2007 56, 27-30DOI: (10.1016/j.jaad.2006.10.048) Copyright © 2007 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Scanning electron microscopy, backscattered electron images of cut surface of paraffin block of skin biopsy, low magnification (A), and detail (B), showing deposition of calcium, phosphorus, sodium, and gadolinium along the basal lamina of eccrine sweat glands. Energy dispersive x-ray spectra show major composition of bright areas is sodium-calcium-phosphate (C), with gadolinium detected at much lower concentrations (D). Journal of the American Academy of Dermatology 2007 56, 27-30DOI: (10.1016/j.jaad.2006.10.048) Copyright © 2007 American Academy of Dermatology, Inc. Terms and Conditions