Fig. 6. Mutational analysis of phospho-residues in hTau.

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inhibits BMP signalling.

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Vegetal RNAs antagonise the dorsalising and BMP-inhibiting activity of Vrtn. Vegetal RNAs antagonise the dorsalising and BMP-inhibiting activity of Vrtn.

Volume 23, Issue 3, Pages (February 2013)

Overexpression of sra exacerbates Aβ42-induced phenotypes in Aβ42-expressing flies. Overexpression of sra exacerbates Aβ42-induced phenotypes in Aβ42-expressing.

Inducible DM1 model displays increased autophagy.

Fig. 5. Tau phospho-epitopes phosphorylated by human GSK3β in the Drosophila visual system.Sarcosyl-soluble and -insoluble Tau fractions were purified.

Fig. 2. Effect of endurance training on gene expression, and protein content and activity in heart muscle. Effect of endurance training on gene expression,

mTOR downregulation, but not autophagy, reduces VAP(P58S) aggregation.

Fig. 3. No increase in Tau-mediated toxicity caused by the R406W mutation.(A) GMR-gal4 driving expression from the 68A integration site of 2N4R or 0N4R.

Fig. 4. Clinically defined SMN mutants show alterations in the association with telomerase complex proteins. Clinically defined SMN mutants show alterations.

Fig. 1. Chlamydia infection causes elevated levels of sortilin.

Fig. 7. Motion adaptation increases time-dependent response modulations (TDRM) relatively to the average cell response.TDRM normalized to the value obtained.

The histidine-rich loop regulates accessibility of the active site and RDEL motif in vivo. The histidine-rich loop regulates accessibility of the active.

Fig. 2. Proportion of motile objects and track length

Fig. 4. A primary screen based on scrape closure

TC-1 silencing sensitized A549 and SPC-A-1 cells to radiation therapy

The effects of laminarin, PMA and zymosan on PKC phosphorylation.

Fig. 4. Expression of miR-2 family mediates tissue growth of Hippo pathway.(A) Photomicrographs of adult wings of the indicated genotype. Expression of.

Inflammation is associated with increased basal-cell plasticity in the Nkx3.1 mutant prostate. Inflammation is associated with increased basal-cell plasticity.

Fig. 1. Exogenous folic acid and Folr1 rescues the function of a Rho-kinase binding mutation in Shroom3. Exogenous folic acid and Folr1 rescues thefunction.

Fig. 5. Expression of either dFMRP or human FMRP does not induce eIF2α phosphorylation.(A) Analysis of eIF2α phosphorylation upon dFMRP expression. Expression.

Fig. 4. Expression of p75NTR and time-course of TrkA autophosphorylation at the Y751 and Y490 sites in PC12-27 cells transfected with the vector, empty.

TP53 western blot of primary cultured tail cells from both wild-type (WT) and Tp53Δ11/Δ11 (−/−) rats. TP53 western blot of primary cultured tail cells.

Survival and telomere length of G2tert−/− zebrafish in a p53−/− background. Survival and telomere length of G2tert−/− zebrafish in a p53−/− background.

eb1a-2 eb1b-3 double-mutant plants display skewed and shorter roots

Fig. 7. E2F1 acetylation in A1/A2-KO MEFs

Fig. 3. Lifetime fecundity and fecundity across age blocks in flies from the selected and control populations emerging in the morning and evening windows.(a)

Fig. 2. Two signal-producing behaviours of wild-type Canton-S males and per mutant males relative to whether the wild-type female is moving or immobile.

Fitm RNAi-1 knockdown in Drosophila interferes with morphology of nociceptive multi-dendritic sensory neurons. Fitm RNAi-1 knockdown in Drosophila interferes.

Fig. 5. Morphological changes of the N

Fig. 6. Effect of SAHA and ML on histone acetylation, BAX, and p21CDKN1A expression.PANC-1 and BxPC-3 cells were incubated for 48 hours with 5 µM.

Fig. 5. Receptor tyrosine kinase activation in response to growth factor stimulation. Receptor tyrosine kinase activation in response to growth factor.

Fig. 2. Centrosomal proteins display distinct localizations and radial distances from centriole walls.U2OS cells were fixed and stained with the indicated.

Fig. 4. One-dimensional gel electrophoresis of DIMs

Fig. 2. Soluble sugar and organic acid levels with different K fertilization during fruit development. Soluble sugar and organic acid levels with different.

Fig. 1. Aboveground biomass of Caragana and herbaceous plants, and proportional abundance of Caragana, under different grazing management treatments. Aboveground.

Fig. 7. Ror-GFP binds to Myc-tagged Wnts and Wnt receptors.

Fig. 3. Reduced histone H3K9 trimethylation in SCNT embryos treated with TSA and VC. (A) Immunostaining analysis indicated that SCNT embryos with TSA+VC.

Fig. 3. Effect of substrate orientation on growth rate for bottom-dwelling tadpoles with similar oral configuration. Effect of substrate orientation on.

The mutants exhibit congenital hypothyroidism.

An inhibitor of HSP90β reduces the level of HNF4A protein in hepatic progenitor cells. An inhibitor of HSP90β reduces the level of HNF4A protein in hepatic.

The idefix phenotype first becomes visible during metamorphosis

Statistical chart of significantly differentially expressed genes

Fig. 4. Quantitative mRNA expression of two membrane-bound trehalase genes in Harmonia axyridis in response to starvation (0–72 h). Quantitative mRNA expression.

Fig. 2. Kinetics of OptoEphB2 activation.

Fig. 3. Enhanced EGFR signaling in Rhbdf2P159L/P159L mice.

Analysis of Cdc7p at the end of meiosis.

Fgfr3;4 mutant lungs display an increase in Mfap5, Igf1 and Fbn2 expression. Fgfr3;4 mutant lungs display an increase in Mfap5,Igf1and Fbn2 expression.

Fig. 6. F1 trβ mutants accomplish natural metamorphosis.

Fig. 2. The Clu and TPR domains are required for Clu function in vivo.

Fig. 3. Effects of Tec on IL-1β-induced apoptosis in chondrocytes.

Fig. 3. Parp mutation rescues mitochondrial function in pink1 mutants.

Amplicon sequencing analysis of on-target sites in trβ crispants

Analysis of mutant Best1 protein (Y227N) in testis and sperm function

Fig. 2. Coupling of actin to cell–cell junctions requires α-catenin and is necessary for the establishment of the barrier.(A) Effect of Cytochalasin D.

miR-145 regulates IGF1R expression.

Fig. 2. Expression of Cx43 mutant T154A resulted in non-radial spreading and formation of protrusions in J558µm3 cells spreading in response to BCR signaling.(A)

Proteus mirabilis strain HI4320 (WT) and isogenic mutants for dsdA, dsdC, or dsdX were cultured in LB broth overnight and diluted 1:100 into fresh LB (A),

Fig. 2. Acetylation stiffens primary cilia.

Fig. 5. Testis defects in STK35 KO mice.

The influence of SHIP2 on cell migration in breast cancer cells.

Fig. 6. RhoB is required for Rnd3-induced stress fibre formation

The vps13 mutants are hypersensitive to SDS but cell wall integrity is not compromised. The vps13 mutants are hypersensitive to SDS but cell wall integrity.

Fig. 1. p85β localizes at adhesion plaques and associates with FAK

Fig. 3. Changes in the total EPS/Chl a ratio and bend interval of trichomes before and after the removal of polysaccharide from the BG11-cultured N. flagelliforme.

Fig. 1. lgl interacts genetically with Argonaute 1 (AGO1) in the eye.

Fig. 7. Analysis of dFMRP kinetics in dFMRP granules by FRAP

Distance between the treated fish and its nearest neighbor increases 1 and 2 weeks after lateral line inactivation. Distance between the treated fish and.

Vps36 interacts with Smo in the absence of Hh

Predictive value of the FGFR3 mutation assay increases with multiple consecutive FGFR3-positive urine samples. Predictive value of the FGFR3 mutation assay.

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Fig. 6. Mutational analysis of phospho-residues in hTau. Mutational analysis of phospho-residues in hTau. (A) hTau2N4R with the different phospho-serines that are known to be targeted by TTBK1, TTBK2 and MARK1. (B) Western blot analysis of mutant UAS-hTau2N4R transgenes driven by the n-Syb-Gal4;Gal80[ts] driver. hTau2N4R was detected using a polyclonal hTau antibody; Syx was used as loading control (two independent experiments, 20 adult heads each). hTauTTBK1S6A displayed faster migration than the other hTau2N4R variants. (C,D) Lifespan analysis of mutant hTau2N4R strains driven by the n-Syb-Gal4;Gal80[ts] driver. Results are depicted as Kaplan–Meier survival curves (D) (Kaplan and Meier, 1958) and bar graph (C). hTau2N4R and hTauTTBK1S6E did not show any toxicity while hTauMARK1S6E toxicity was significant when compared to control flies (n-Syb-Gal4;Gal80[ts] crossed to the attP landing site strain BL#9750; error bars indicate mean±s.d.; ***P≤0.001; Dunnett's multiple comparison; n=3 independent experiments; ≥96 flies). Josefin Fernius et al. Biology Open 2017;6:1013-1023 © 2017. Published by The Company of Biologists Ltd