Fig. 4. Deletion of Baf60c in myocardium results in dilated chambers and impaired cardiac function. Deletion of Baf60c in myocardium results in dilated.

Slides:

Advertisements

Similar presentations

Journal of Molecular and Cellular Cardiology

Advertisements

by Simon F. De Meyer, Alexander S. Savchenko, Michael S

The pathophysiological processes linked to kidney disease.

Hironori Hara et al. BTS 2018;3:

Collagen accumulation is reduced with UK

Sebastiano Sciarretta et al. JACC 2018;71:

Fig. 5. Prip silencing enhances the co-localization of GABARAP with insulin vesicles and β-tubulin.Co-localization of GABARAP (green) with insulin (red)

Fig. 1. Overview of the nervous system of the adult S. roscoffensis.

Loss of Setdb1 in early B cells leads to impaired B cell development.

Fig. 2. Outline of the two types of stimulus sequences employed in the analysis.(A) Environment information stimuli; (B) adaptation stimuli. Outline of.

Fig. 8. In vitro effect of CMPs on adult DSS-treated stomach explants.

Fig. 8. CCA and ChQ treatment induce accumulation of F-actin rings.

Fig. 1. Representative images of the four cell lines using fluorescence microscopy. Representative images of the four cell lines using fluorescence microscopy.

Arterial Notch signaling is not required for artery patterning.

Differential Cre-ERT activity and PTEN deletion in endometrial epithelial and stromal compartments. Differential Cre-ERT activity and PTEN deletion in.

Fig. 2. Proportion of motile objects and track length

Fig. 1. Muscle-specific PITX1 over-expression in the Pitx1 transgenic mice.(A) Detection of Pitx1 mRNA expression in muscles of the Pitx1 transgenic mice.

TC-1 silencing sensitized A549 and SPC-A-1 cells to radiation therapy

Tomoregulin-1 improves cardiac pathological changes after pressure overload. Tomoregulin-1 improves cardiac pathological changes after pressure overload.

OCT and IOP analysis of 2-3-month-old AP-2β NCC KO mutants.

Fig. 2. Body weight and size analysis of A1/A2-KO mice

Fig. 1. Mitochondrial internalization in cardiomyocytes.

Fig. 5. Onecut transcription factors are important for the correct generation of the mdDA neuronal population.(A) Schematic representation of the region.

Fig. 6. Schematic diagram showing distribution and dynamics of four E-cadherin populations within the ROI of a FRAP experiment. Schematic diagram showing.

Fig. 1. Lack of Hmga1 and Hmga2 expression in A1/A2-KO mice

Fig. 4. The model of malate metabolism in fruit cells under different K level conditions. The model of malate metabolism in fruit cells under different.

Expression of tomoregulin-1 in wild-type and cardiac hypertrophy mouse myocardium. Expression of tomoregulin-1 in wild-type and cardiac hypertrophy mouse.

Fig. 2. Salivary glands from RasV12-expressing larvae produce MMP1, release tissue fragments into the hemolymph and express apoptotic markers.Salivary.

Fig. 1. γ-Tubulin localizes in close proximity to centriole walls in interphase but within an extended PCM meshwork in mitosis.U2OS cells were fixed and.

Fig. 7. E2F1 acetylation in A1/A2-KO MEFs

Fig. 3. Mutation of Y520 and Y667 result in increased delivery of prestin to the apical surface of MDCK cells.MDCK cells transiently transfected with wt.

Formation of papilloma lesions in the UroIICre+Fgfr3+/K644EK-RasG12D/+ model. Formation of papilloma lesions in theUroIICre+Fgfr3+/K644EK-RasG12D/+model.

Fcp1 CTD phosphatase affects a broad range of transcripts in the +N and -N media. Fcp1 CTD phosphatase affects a broad range of transcripts in the +N and.

Fig. 2. Ex vivo inducible knockout of PDCD2 in ESCs results in loss of S phase entry and increased p53.(A) Growth curve of inducible knockout and WT ESCs.

P53 is responsible for the induction of apoptosis, developmental malformations and mortality of G1 and G2tert mutant zebrafish. p53 is responsible for.

Fig. 7. Interaction between BAF60c and cardiac transcription factors.

Fig. 7. Lhx1-RNAi reduces the eye size

Adult cardiomyocyte renewal via deletion of Hippo pathway genes.

Fig. 2. Centrosomal proteins display distinct localizations and radial distances from centriole walls.U2OS cells were fixed and stained with the indicated.

Fig. 2. Soluble sugar and organic acid levels with different K fertilization during fruit development. Soluble sugar and organic acid levels with different.

Fig. 4. BKA values for different species.

Fig. 1. Generation of WNK3 knockout mice

Kmt2b is required for SSC-to-progenitor transition.

Fig. 7. Representative images of control (Cas9+GFP) and Cas9+gRNA+GFP co-injected embryos on day 4 of culture, showing nuclear-imported GFP (green) and.

Detection of nuclear foci by FISH on frozen sections of diaphragm muscle prepared from 2-month-old DMSXL mice. Detection of nuclear foci by FISH on frozen.

Fig. 6. STK35 KO mice show ovary defects.

Fig. 4. CIZ1 reduces the impact of injury to the heart.

Fig. 2. mip120 null mutants have abnormal egg chamber development.

Characterization of zebrafish muscle wasting in krasG12V-induced HCC zebrafish. 4-month-old male adult krasG12V and WT zebrafish were treated with dox.

Cellular reaction to intraventricular DMSO injection.

Fig. 2. Sufficient rate of recombination in embryonic NSCs and NPCs of Emx1cre knock-in mice.(A) Breeding schemes to generate mice with the Emx1cre locus.

BAF60c transcriptionally affects cardiac morphogenesis and function

Gα12 is not required for hepatic cystogenosis induced by Pkd1 knockout

Fig. 2. iPSCs produce functional osteoblasts.

Analysis of mutant Best1 protein (Y227N) in testis and sperm function

Vessel density is decreased in tumors grown in Fbln5−/− mice.

Altered intracellular distributions of acetylated α-tubulin, mitochondria and peroxisomes. Altered intracellular distributions of acetylated α-tubulin,

Fig. 5. Testis defects in STK35 KO mice.

Fig. 3. Mean force and velocity during jumping

Nutrient availability regulates growth of the X. laevis optic tectum.

mip120 null egg chambers have a condensed nurse cell DNA phenotype

Integrin-mediated signaling is required for PFC maturation.

Adult Acvr1;Trp53DCKO lenses form vascularized, tumor-like structures at their posterior poles. 4-month-old Trp53CKO and Acvr1;Trp53DCKO lenses were sectioned.

Fig. 7. Nrf2-dependent enzyme activities in wild-type, Nrf2- and Keap1-deficient tissues.Hepatic (A,C,E) and cortical (B,D,F) enzyme activities of NQO1.

Fig. 5. Behaviours of the wild-types Oregon-R at two temperatures.

Fig. 1. lgl interacts genetically with Argonaute 1 (AGO1) in the eye.

The absence of host Fbln5 results in increased apoptosis and decreased proliferation in Pan02 tumors. The absence of host Fbln5 results in increased apoptosis.

Two REMS-like iterations demonstrating common patterns of rapid brightness changes of skin patterning. Two REMS-like iterations demonstrating common patterns.

2DG suppresses of lamellipodia and filopodia and causes disorganization of F-actin filaments in murine endothelial cells. 2DG suppresses of lamellipodia.

PC loss in Nhe6-null mouse cerebellum, female and male.

Presentation transcript:

Fig. 4. Deletion of Baf60c in myocardium results in dilated chambers and impaired cardiac function. Deletion of Baf60c in myocardium results in dilated chambers and impaired cardiac function. (A) Baf60cfl/−;Myh6::Cre mice all die before 4 months of age. Fraction of remaining mice of each genotype is graphed. Initial number was 129 (37 flox/+, 36 flox/+;Cre, 26 flox/-, 30 flox/-;Cre). (B) Baf60cfl/−;Myh6::Cre mice have enlarged hearts and dilated chambers, as shown with whole-mount (top panel) and four-chamber view sections (middle panel). Left panel: P10. Right panel: 8-week hearts. Masson trichrome staining detects fibrosis in ventricle myocardium (bottom panels, arrowheads). (C) Baf60cMyh6KO myocardium have high levels of apoptosis. Green, TUNEL; blue, DAPI. (D) Representative electrocardiogram of adult WT and Baf60cfl/−;Myh6::Cre mice. Xin Sun et al. Biology Open 2018;7:bio029512 © 2018. Published by The Company of Biologists Ltd