The correlation network constructed using the identified metagenomic species (MGS), metabolic parameters (including TGs, TC, and FPG), SCFAs (including.

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The correlation network constructed using the identified metagenomic species (MGS), metabolic parameters (including TGs, TC, and FPG), SCFAs (including acetic, propionic, butyric, and valeric acid), gut-brain mediators (PYY and ghrelin), and sex hormones (including LH, FSH, LH/FSH, E2, PRL, and T) based on Spearman's rank correlation coefficient (R greater than 0.4 or R less than −0.4). The correlation network constructed using the identified metagenomic species (MGS), metabolic parameters (including TGs, TC, and FPG), SCFAs (including acetic, propionic, butyric, and valeric acid), gut-brain mediators (PYY and ghrelin), and sex hormones (including LH, FSH, LH/FSH, E2, PRL, and T) based on Spearman's rank correlation coefficient (R greater than 0.4 or R less than −0.4). The edge width and color (red, positive; green, negative) are proportional to the strength of the correlation. The node size is proportional to the mean abundance in the respective population. Nodes with the same color are classified as the same type of indicators. Bif, Bifidobacterium. Jiachao Zhang et al. mSystems 2019; doi:10.1128/mSystems.00017-19