Graft-preserving treatment for vascular graft infected with Staphylococcus aureus with antibiotic-releasing porous apatite ceramic in the rabbit Katsutoshi.

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Graft-preserving treatment for vascular graft infected with Staphylococcus aureus with antibiotic-releasing porous apatite ceramic in the rabbit Katsutoshi Murase, MD, Hajime Hirose, MD, PhD, Yoshio Mori, MD, PhD, Hisato Takagi, MD, PhD, Hisashi Iwata, MD, PhD, Tetsu Sago, MD, Yoshiaki Kawamura, PhD Journal of Vascular Surgery Volume 38, Issue 2, Pages 368-373 (August 2003) DOI: 10.1016/S0741-5214(03)00120-4

Fig 1 Infected graft. A, Retroperitoneal abscess around patch graft (arrow) on day 7. B, Patch graft (arrow) after debridement of infected tissue. C, After debridement, antibiotic-loaded β-tricalcium phosphate block (arrow) was placed straddling the patch graft. Journal of Vascular Surgery 2003 38, 368-373DOI: (10.1016/S0741-5214(03)00120-4)

Fig 2 In vivo study showed that teicoplanin (TEIC) concentration in replaced saline solution remained above minimum inhibitory concentration for Staphylococcus aureus for 28 days. Journal of Vascular Surgery 2003 38, 368-373DOI: (10.1016/S0741-5214(03)00120-4)