President’s Report A.E. Karakaya Montreal, 18 July 2007 General Assembly President’s Report A.E. Karakaya Montreal, 18 July 2007

IUTOX EXECUTIVE COMMITTEE (2004-2007) President Ali Esat Karakaya (Turkey) President-Elect Robert Kroes (The Netherlands) Vice President Tohru Inoue (Japan) Secretary General Wallace Hayes (USA) Treasurer Alexander Buerkle (Germany) Director Corrado Galli (Italy) Director Kevin Chipman (UK) Director Silvia Moraes Barros (Brazil) Director Barbara Hales (Canada) Director Konrad Rydzynski (Poland)

IUTOX President Elect (2004-2007 Term) Prof. Robert Kroes 1940 – 2006 .

2004 TAMPERE GENERAL ASSEMBLY: MAIN DECISIONS 4 important changes in by-laws were made at the 2004 Tampere IUTOX General Assembly. The Congresses of Toxicology in Developing Countries. (CTDCs) have been integrated into the IUTOX activities. The Developing Countries Committee has been established as a Standing Committee. Institutional Memberships has been established. Past-President position in the Executive Committee has been abolished.

THE FIRST EC MEETING in TAMPERE: MAIN DECISIONS Two Task Forces Have Been Established. *Task Force for Harmonization of the Certification/Registration of Toxicologists. *Task Force for the Enhancement of the Appreciation and Image of Toxicology. Committees / Commissions Have Been Formed and Started Work on 2004-2007 IUTOX Strategic Plan.

IUTOX TASK FORCES Task Force for Harmonization of the Certification/ Registration of Toxicologists. Chair: Corrado Galli (Italy). Members: Silvia Barros (Brazil), Wallace Hayes (USA), Tetsuo Satoh (Japan). Task Force for the Enhancement of the Appreciation and Image of Toxicology. Chair: Kevin Chipman (UK). Members: Robert Kroes (The Netherlands), Konrad Rydzynski (Poland), Linda Birnbaum (SOT), Maritza R. Martini (ALATOX), Tetsuo Satoh ( ASIATOX).

IUTOX Standing Committees Membership Committee: Chair: Tohru Inoue (Japan). Members: Silvia Barros (Brazil), Konrad Rydzynki (Poland). Developing Countries Committee: Chair: Silvia Barros (Brazil). Members: Mary Gulumian (S. Africa), Sunshi Chen (China), George Corcoran (USA), Edmond Creppy (France), Wallace Hayes(USA), Jyrki Liesivuori (Finland), Angelika Tritscher (WHO).

2004-2007 IUTOX Commissions Finance Commission: Chair: Alexander Buerkle (Germany) Members: Robert Kroes (The Netherlands), A. Wallace Hayes (USA) Education and Career Development Commission: Chair: Kevin Chipman (UK) Members: Barbara Hales (Canada), Wallace Hayes (USA), Corrado Galli (Italy) Paul Wright (Australia) Communication Commission: Chair: Wallace Hayes (USA), Members: Corrado Galli (Italy), Konrad Rydzynki (Poland), Paul Wright (Australia). Scientific Commission: Chair: Robert Kroes (The Netherlands) / Barbara Hales (Canada). Members: Kevin Chipman (UK), Tohru Inoue (Japan).

2004-2007 IUTOX STRATEGIC PLAN The Following Were Taken into Account in the preparation of the Strategic Plan. * IUTOX Mission and Long Range Goals * Plans of the Committees /Commissions and Task Forces. * Strategic Plans of the Previous Terms. The Strategic Plan Was Finalized in September 2004 and Announced on the IUTOX Web-site.

www.iutox.org/strategic.asp.

2004-2007 IUTOX STRATEGIC PLAN: Objectives Have Been Actualized As the IUTOX Executive Committee, we are pleased to report that the objectives in the 2004-2007 Strategic Plan have been actualized as had been planned.

Society Growth Number of Societies 1980 1998 2001 2004 2007

Membership Growth 1998 2001 2007

New Member Societies since 2004 Academy of Toxicological Sciences  Austrian Society of Toxicology  Portuguese Pharmacological Society  Cuban Society of Toxicology   Ukrainian Toxicology Society 14

IUTOX MEMBER SOCIETIES REGIONAL SOCIETIES and INTERNATIONAL ASSOCIATIONS (7 members) ASIATOX EUROTOX Latin American Association of Toxicology Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Academy of Toxicological Sciences European Association of Poison Centers and Clinical Toxicology International Neurotoxicology Association 15

IUTOX Member Societies-2 EUROPE (26 National Societies) Austrian Society of Toxicology British Toxicology Society Bulgarian Society of Toxicology Croatian Toxicological Society Danish Society of Pharmacology and Toxicology Estonian Society of Toxicology Finnish Society of Toxicology French Society of Clinical Toxicology French Society of Toxicology German Society for Experimental and Clinical Pharmacology and Toxicology Hellenic Society of Toxicology Irish Society of Toxicology Italian Society of Toxicology Latvian Society of Toxicology Netherlands Society of Toxicology Norwegian Society of Pharmacology and Toxicology Polish Society of Toxicology Portuguese Pharmacological Society Russian Society of Toxicology Slovenian Society of Toxicology Spanish Society of Toxicology Swedish Society of Toxicology Swiss Society of Pharmacology and Toxicology Turkish Society of Toxicology Ukrainian Toxicology Society Union of Hungarian Toxicologists 16

IUTOX Member Societies-3 NORTH AMERICA (4 members) American Academy of Clinical Toxicology American College of Toxicology Society of Toxicology, USA Society of Toxicology of Canada LATIN AMERICA (4 members) Argentina Toxicology Association Brazilian Society of Toxicology Cuban Society of Toxicology Mexican Society of Toxicology AFRICA (2 members) Egyptian Society of Toxicology South African Society of Toxicology 17

IUTOX Member Societies-4 ASIA (9 National Societies) Chinese Society of Toxicology Israeli Society of Toxicology Iranian Society of Toxicology Japanese Society of Clinical Toxicology Japanese Society of Toxicology Korean Society of Toxicology Society of Toxicology, India Society of Toxicology of Taiwan Toxicological Society of Thailand 18

Institutional Members AMGEN Cantox Health Science International Chevron Phillips Chemical Environ International GlaxoSmithKline Johnson & Johnson Pharmaceutical Research & Development L'OREAL Pfizer Global Research and Development TAP Pharmaceutical Products

Selected Scientific and Educational Activities International Congresses of Toxicology (ICT) Congresses of Toxicology in Developing Countries (CTDC) Risk Assessment Summer Schools (RASS) Continuing Education Courses in Developing Countries Grants and Fellowship Programs for Toxicologists from Developing Countries Participation in International Scientific Projects

SOPs and Guidelines Have Been Prepared for IUTOX Activites Standard Operating Procedures (SOPs) Executive Committee Nominating Process ICT and CTDC Congresses Guidelines for Other Activities

Capacity Building in Toxicology in Developing Countries - CTDCs 6th Congress of Toxicology in Developing Countries (6th CTDC) successfully held in Croatia in 2006 as an integrated meeting with the 43rd Congress of the European Societies of Toxicology. 7th CDTC will be held in Sun City, South Africa in 2009 and work regarding the organization of this congress has already started in cooperation with the South African Society.

Capacity Building in Toxicology in Developing Countries – Fellowship Program Fellowships; Support participation in the IUTOX congresses (ICT and CTDC) and the SOT meetings 83 junior and senior scientists from 29 developing countries: * 27 AstraZeneca -SOT Awards for 2005,2006, 2007 SOT meetings. *19 Fellowships for 2006 CTDC *37 fellowships for 2007 ICT XI 23

Capacity Building in Toxicology in Developing Countries – Sponsored Lectures Program Meeting Support in Developing Countries India 2004 China 2005 Argentina 2005 Estonia 2006 China 2006 Mexico 2006 Chile 2006 South Africa 2006 Nigeria 2006

ICTs The flagship of IUTOX is the ICT IUTOX has worked in close cooperation with the Society of Toxicology Canada for the organization of the ICT XI Montreal 2007 Meeting. Preparation for ICT XII Barcelona 2010 Meeting has already begun.

Risk Assessment Summer School (RASS) Leadership of Torbjörn Malmfors (with assistance from Birgitta Lewander). Biannually since 1985. Annually since 2004. 75 young postdoctoral toxicologists (2004-2007). 31 participants from 19 nineteen developing countries have been fonded.

TASK FORCES 2004-2007 EC recommends continuation of Task Force for Harmonization of the Certification/Registration of Toxicologists Task Force for the Enhancement of the Appreciation and Image of Toxicology Founded in 2004

Annual Budgetary Deficit is not Sustainable WHAT CAN WE DO? Seek ways to obtain more revunues from ICT and CTDC congresses. Recruiting many more institutional members. Adjust IUTOX dues structure. Reduce expenditures.

IUTOX History

Thanks Many thanks to all of you for your collaboration and warm friendship during my presidency.