Volume 55, Issue 3, Pages 1097-1103 (March 1999) Activation of the kallikrein-kinin system in hemodialysis: Role of membrane electronegativity, blood dilution, and pH Jean-Louis Renaux, Michel Thomas, Thierry Crost, Nathalie Loughraieb, Georges Vantard Kidney International Volume 55, Issue 3, Pages 1097-1103 (March 1999) DOI: 10.1046/j.1523-1755.1999.0550031097.x Copyright © 1999 International Society of Nephrology Terms and Conditions
Figure 1 Effects of plasma dilution on the kallikrein activity measured in undiluted (▪) and 1/20 diluted (•) plasma after a 20 min circulation on AN69 membrane. Each point represents the mean ± SD of measurements on 6 different plasmas, in both experimental conditions (***P < 0.001 vs. undiluted plasma). Kidney International 1999 55, 1097-1103DOI: (10.1046/j.1523-1755.1999.0550031097.x) Copyright © 1999 International Society of Nephrology Terms and Conditions
Figure 2 Kallikrein activity measured in diluted plasma equilibrated at four different pH values after a four (□), six (▪) and 10 () minute circulation through AN69 minidialyzers. Results are mean ± SD for N = 6 different experiments. **P < 0.01 for pH 7.1 vs. pH 7.4, 7.6 and 7.8 at every contact time; †P < 0.05 for pH 7.4 vs. pH 7.6 and 7.8 at 6 and 10 min. Kidney International 1999 55, 1097-1103DOI: (10.1046/j.1523-1755.1999.0550031097.x) Copyright © 1999 International Society of Nephrology Terms and Conditions
Kidney International 1999 55, 1097-1103DOI: (10. 1046/j. 1523-1755 Kidney International 1999 55, 1097-1103DOI: (10.1046/j.1523-1755.1999.0550031097.x) Copyright © 1999 International Society of Nephrology Terms and Conditions