Bacteriophages: How Bacterial Spores Capture and Protect Phage DNA

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Bacteriophages: How Bacterial Spores Capture and Protect Phage DNA Abraham L. Sonenshein  Current Biology  Volume 16, Issue 1, Pages R14-R16 (January 2006) DOI: 10.1016/j.cub.2005.12.007 Copyright © 2006 Elsevier Ltd Terms and Conditions

Figure 1 Fate of phage DNA during infection of growing (vegetative) and sporulating cells of B. subtilis. Injection of phage DNA into vegetative cells leads to phage gene expression, replication of phage DNA, assembly of phage particles and lysis of the host cell. During infection of sporulating cells, phage gene expression is excluded and the unreplicated phage DNA has the potential to be incorporated into the developing spore. If placed in a nutrient-rich environment, the infected spore will germinate and support expression and replication of the trapped phage DNA, leading to lysis and phage release. (Drawn by K. Pechter.) Current Biology 2006 16, R14-R16DOI: (10.1016/j.cub.2005.12.007) Copyright © 2006 Elsevier Ltd Terms and Conditions